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peroxisome proliferator activated receptor alpha
Summary
- Gene Symbol
-
- PPARA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Biological rhythms
- DNA-binding
- Lipid-binding
- Nucleus
- Receptor
- Reference proteome
- Transcription regulation
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of fatty acid beta-oxidation | ||
| nitric oxide metabolic process | ||
| negative regulation of signaling receptor activity | ||
| negative regulation of glycolytic process | ||
| wound healing |
GO Hierarchy
- regulation of circadian rhythm
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| zinc ion binding | ||
| DNA-binding transcription factor binding |
|
|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- nuclear receptor subfamily 1, group D, member 1
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell differentiation |
| hormone-mediated signaling pathway |
| intracellular receptor signaling pathway |
| metal ion binding |
| sequence-specific DNA binding |
| zinc ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:10908 | hydrocephalus | |
| DOID:12351 | alcoholic hepatitis | |
| DOID:1485 | cystic fibrosis | |
| DOID:3146 | lipid metabolism disorder | |
| DOID:3393 | coronary artery disease | |
| DOID:5419 | schizophrenia | |
| DOID:5844 | myocardial infarction | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100917093 | SARHA04309 | |||
| 100943292 | OTOGA17304 | |||
| 100975411 | 9597_0:005442 | PANPA24083 | ||
| 101011461 | PAPAN12817 | |||
| 101032215 | SAIBB20863 | |||
| 101095837 | FELCA15801 | |||
| 101146658 | 9595_0:00558b | GORGO24396 | ||
| 101335590 | TURTR15173 | |||
| 101566900 | OCTDE21225 | |||
| 101595681 | JACJA01566 |
