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transmembrane p24 trafficking protein 9

Summary

Gene Symbol

TMED9

Aliases

HSGP25L2G
p24a2
p24alpha2

Organism

Homo sapiens (human)

External Links

NCBI Gene

54732

HGNC

24878

KEGG Gene ID

hsa:54732

PubChem

54732

Alliance of Genome Resources

HGNC:24878

Annotation

Keyword

Acetylation
Coiled coil
Direct protein sequencing
Endoplasmic reticulum
Glycoprotein
Golgi apparatus
Protein transport
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9BVK6	GMP25 Glycoprotein 25L2 p24 family protein alpha-2 p25

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
Golgi organization	IBA IMP	18287528
COPI coating of Golgi vesicle	IBA IMP	18287528
positive regulation of organelle organization	IMP	18287528
endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
early endosome to Golgi transport	IMP	18287528

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

endoplasmic reticulum to Golgi vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

vesicle organization [inference]

vesicle coating [inference]

Golgi transport vesicle coating [inference]

COPI coating of Golgi vesicle

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

intracellular transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

endoplasmic reticulum to Golgi vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

endoplasmic reticulum to Golgi vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

endoplasmic reticulum to Golgi vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

protein exit from endoplasmic reticulum

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization

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GO Term	Evidence Code	PMID
endoplasmic reticulum-Golgi intermediate compartment membrane
COPII-coated ER to Golgi transport vesicle	IBA
endoplasmic reticulum-Golgi intermediate compartment	IBA IDA	12237308
endoplasmic reticulum	IBA IDA	12237308
transport vesicle

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle

trans-Golgi network transport vesicle

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle

trans-Golgi network transport vesicle

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle

trans-Golgi network transport vesicle

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cargo receptor activity	IBA
syntaxin binding	IPI	21545355
protein binding	IPI	16595549 32296183

GO Hierarchy

molecular function

binding [inference]

protein binding

SNARE binding [inference]

syntaxin binding

cargo receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000184840

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K20346

Name

p24 family protein alpha

References

10852829

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050387	nonpapillary renal cell carcinoma	DisGeNET
DOID:0050523	adult T-cell leukemia/lymphoma	DisGeNET
DOID:0050635	alternating hemiplegia of childhood	DisGeNET
DOID:0060162	dentatorubral-pallidoluysian atrophy	DisGeNET
DOID:0060193	amyotrophic lateral sclerosis type 1	DisGeNET
DOID:0060194	amyotrophic lateral sclerosis type 2	DisGeNET
DOID:0060196	amyotrophic lateral sclerosis type 4	DisGeNET
DOID:0060672	Grn-related frontotemporal lobar degeneration with Tdp43 inclusions	DisGeNET
DOID:0060891	Parkinson's disease 19A	DisGeNET
DOID:0060895	Parkinson's disease 4	DisGeNET

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	180307	WB:WBGene00013360
Drosophila melanogaster	41177	FB:FBgn0069242
Drosophila melanogaster	318890	FB:FBgn0053105
Latimeria chalumnae	102354138		LATCH16133
Danio rerio	613145	ZFIN:ZDB-GENE-050417-434	DANRE06577
Astyanax mexicanus	103030438		ASTMX04738
Ictalurus punctatus	108269151		ICTPU34085
Electrophorus electricus	113573386		ELEEL13241
Salmo trutta	115167339		SALTR42769
Salmo trutta	115205711		SALTR111256

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements