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creatine kinase, mitochondrial 1A

Summary

Gene Symbol

CKMT1A

Organism

Homo sapiens (human)

External Links

NCBI Gene

548596

PubChem

548596

Alliance of Genome Resources

HGNC:31736

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Kinase
Mitochondrion inner membrane
Phosphoprotein
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
P12532	Acidic-type mitochondrial creatine kinase Ubiquitous mitochondrial creatine kinase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
phosphocreatine biosynthetic process	IBA
phosphorylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

phosphorylation

organophosphate metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organophosphate biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organophosphate biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

phosphorylation

organophosphate metabolic process [inference]

phosphagen metabolic process [inference]

phosphocreatine metabolic process [inference]

phosphocreatine biosynthetic process

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

organophosphate biosynthetic process [inference]

phosphagen biosynthetic process [inference]

phosphocreatine biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	TAS
mitochondrion	HTP IBA	34800366

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183 32814053 33961781
creatine kinase activity	IBA
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

creatine kinase activity

phosphotransferase activity, nitrogenous group as acceptor [inference]

creatine kinase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

creatine kinase

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
catalytic activity
creatine kinase activity
kinase activity
nucleotide binding
phosphocreatine biosynthetic process
phosphorylation
transferase activity, transferring phosphorus-containing groups
transferase activity

Displaying **all 6** entries
InterPro
ATP
ATP
ATP
ATP
ATP
Glutamine synthetase/guanido kinase, catalytic domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1824	status epilepticus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	12716		MGI:99441	MOUSE32518
Rattus norvegicus	29593		RGD:61976	RATNO28472
Drosophila melanogaster	39040		FB:FBgn0035957
Drosophila melanogaster	39041		FB:FBgn0000116
Drosophila melanogaster	41922		FB:FBgn0038373
Caenorhabditis elegans	171831		WB:WBGene00017975
Caenorhabditis elegans	171850		WB:WBGene00021128
Caenorhabditis elegans	172907		WB:WBGene00013894
Caenorhabditis elegans	180080		WB:WBGene00009706
Bos taurus	281692			BOVIN16857

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Last updated: December 9, 2024