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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NOP2/Sun RNA methyltransferase 2
Summary
- Gene Symbol
-
- NSUN2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Cytoskeleton
- Direct protein sequencing
- Disease variant
- Intellectual disability
- Isopeptide bond
- Methyltransferase
- Mitochondrion
- Mitosis
- Nucleus
- Phosphoprotein
- Reference proteome
- S-adenosyl-L-methionine
- Secreted
- Spermatogenesis
- Ubl conjugation
- tRNA processing
- tRNA-binding
- Proteins
| UniProt | Protein Name |
|---|---|
| Q08J23 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of mRNA export from nucleus | ||
| hair follicle maturation | ||
| meiotic cell cycle checkpoint signaling | ||
| tRNA modification | ||
| spermatid development |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| spindle | ||
| nucleoplasm | ||
| mitochondrion | ||
| chromatoid body | ||
| nucleus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| tRNA (cytidine-5-)-methyltransferase activity | ||
| tRNA binding | ||
| mRNA (cytidine-5-)-methyltransferase activity | ||
| RNA binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Methyltransferase
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- L: Replication, recombination and repair
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081181 | autosomal recessive intellectual developmental disorder 5 | |
| DOID:1059 | intellectual disability |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 28114 | MGI:107252 | MOUSE10423 | ||
| 45064 | FB:FBgn0026079 | |||
| 171697 | WB:WBGene00021686 | |||
| 325292 | ZFIN:ZDB-GENE-030131-4017 | DANRE15820 | ||
| 361191 | RGD:1311954 | RATNO16315 | ||
| 414460 | Xenbase:XB-GENE-962628 | |||
| 461711 | 9598_0:001982 | PANTR35022 | ||
| 478625 | CANLF13453 | |||
| 516044 | BOVIN16195 | |||
| 548716 | Xenbase:XB-GENE-962623 |
