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transmembrane protein 260

Summary

Gene Symbol

TMEM260

Organism

Homo sapiens (human)

External Links

NCBI Gene

54916

PubChem

54916

Alliance of Genome Resources

HGNC:20185

Annotation

Keyword

Alternative splicing
Disease variant
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KN73
Q9NX78	Transmembrane protein 260

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein maturation	IDA	37186866
protein O-linked mannosylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

protein maturation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

protein maturation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

protein maturation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

protein maturation

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IDA	37186866

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
dolichyl-phosphate-mannose-protein mannosyltransferase activity	IDA	37186866

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

mannosyltransferase activity [inference]

dolichyl-phosphate-mannose-protein mannosyltransferase activity

catalytic activity, acting on a protein [inference]

dolichyl-phosphate-mannose-protein mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **11 - 16** of 16 in total

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DO ID	Disease Name	Source
DOID:4766	embryoma	DisGeNET
DOID:6406	double outlet right ventricle	DisGeNET
DOID:707	B-cell lymphoma	DisGeNET
DOID:8538	reticulosarcoma	DisGeNET
DOID:8675	obsolete ymphosarcoma	DisGeNET
DOID:9119	acute myeloid leukemia	DisGeNET

Ortholog

Displaying entries **31 - 40** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Panthera leo	122222745		PANLE19812
Tursiops truncatus	101318010		TURTR12490
Balaenoptera musculus	118890116		BALMU30396
Loxodonta africana	100665877		LOXAF15944
Equus caballus	100057780		HORSE23355
Sus scrofa	100512450		PIGXX15207
Bos taurus	614796		BOVIN01466
Capra hircus	102189130		CAPHI00369
Ovis aries	101120752		SHEEP18316
Oryctolagus cuniculus	100351190		RABIT06555

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024