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tRNA methyltransferase 12 homolog

Summary

Gene Symbol

TRMT12

Organism

Homo sapiens (human)

External Links

NCBI Gene

55039

PubChem

55039

Alliance of Genome Resources

HGNC:26091

Annotation

Keyword

Reference proteome
S-adenosyl-L-methionine
Transferase
tRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q53H54	tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
wybutosine biosynthetic process	IBA
tRNA methylation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

organonitrogen compound metabolic process [inference]

wybutosine metabolic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

tRNA methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

macromolecule methylation [inference]

RNA methylation [inference]

tRNA methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

glycosyl compound metabolic process [inference]

wybutosine metabolic process [inference]

wybutosine biosynthetic process

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

organonitrogen compound metabolic process [inference]

wybutosine metabolic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation

tRNA modification [inference]

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25416956 32296183
tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity	IEA
tRNA methyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

RNA methyltransferase activity [inference]

tRNA methyltransferase activity

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA methyltransferase activity [inference]

tRNA methyltransferase activity

catalytic activity, acting on a tRNA [inference]

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Methyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 8** entries
Gene Ontology
methylation
mitochondrial tRNA methylation
tRNA (guanine(37)-N1)-methyltransferase activity
tRNA N1-guanine methylation
tRNA methylation
tRNA methyltransferase activity
tRNA processing
transferase activity

Displaying **all 3** entries
InterPro
S-adenosyl-L-methionine-dependent methyltransferase superfamily
SAM-dependent methyltransferase TRM5/TYW2-type
tRNA (guanine(37)-N(1))-methyltransferase, eukaryotic

Ortholog

Displaying entries **1 - 10** of 53 in total

1

2

3

4

5

6

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	68260		MGI:1915510	MOUSE15134
Caenorhabditis elegans	179363		WB:WBGene00009586
Rattus norvegicus	314999		RGD:1307127	RATNO37027
Pan troglodytes	464377	9598_0:00268e
Bos taurus	516516			BOVIN05754
Danio rerio	564925		ZFIN:ZDB-GENE-060825-182	DANRE07194
Macaca mulatta	705848			MACMU43421
Saccharomyces cerevisiae S288C	855008		SGD:S000004464
Monodelphis domestica	100020165			MONDO19549
Ornithorhynchus anatinus	100087951			ORNAN23057

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Last updated: December 9, 2024