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MIRAGE

RPA1 related single stranded DNA binding protein, X-linked

Summary

Gene Symbol

RADX

Organism

Homo sapiens (human)

External Links

NCBI Gene

55086

PubChem

55086

Alliance of Genome Resources

HGNC:25486

JoGo

RADX

TogoVar

RADX

Annotation

Keyword

3D-structure
Alternative splicing
Chromosome
DNA-binding
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6NSI4	RPA-related and RAD51-antagonist, X-chromosome

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
regulation of DNA repair	IBA
negative regulation of double-strand break repair via homologous recombination	IDA	28735897

GO Hierarchy

biological process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA repair

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA repair

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA repair

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA repair

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of response to stimulus [inference]

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA repair

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of cellular response to stress [inference]

regulation of DNA repair

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

Displaying **all 3** entries
GO Term	Evidence Code	PMID
replication fork	IDA	28735897
replication fork	IBA
nuclear speck	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

replication fork

nuclear body [inference]

nuclear speck

Displaying **all 4** entries
GO Term	Evidence Code	PMID
single-stranded DNA binding	IDA	28735897
single-stranded DNA binding	IBA
RNA binding	HDA	22681889
protein binding	IPI	21516116 25036637 25416956 27229929 31515488 32296183

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

single-stranded DNA binding

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026