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dynein axonemal assembly factor 2

Summary

Gene Symbol

DNAAF2

Organism

Homo sapiens (human)

External Links

NCBI Gene

55172

PubChem

55172

Alliance of Genome Resources

HGNC:20188

Annotation

Keyword

Alternative splicing
Cytoplasm
Kartagener syndrome
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NVR5	Dynein assembly factor 2, axonemal

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
establishment of left/right asymmetry	IEA
inner dynein arm assembly	IEA
response to retinoic acid	IEA
in utero embryonic development	IEA
outer dynein arm assembly	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

epithelial cilium movement involved in extracellular fluid movement

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry [inference]

establishment of left/right asymmetry

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to lipid [inference]

response to retinoic acid

response to oxygen-containing compound [inference]

response to retinoic acid

localization [inference]

establishment of localization [inference]

transport [inference]

extracellular transport [inference]

epithelial cilium movement involved in extracellular fluid movement

microtubule-based transport [inference]

epithelial cilium movement involved in extracellular fluid movement

establishment of localization in cell

biological regulation [inference]

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
protein folding chaperone complex	IPI	29844425
cytosol	IDA
cytoplasm	IBA IDA	19052621
dynein axonemal particle	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

protein folding chaperone complex

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

dynein axonemal particle

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

dynein axonemal particle

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	23872636 27173435 28041644 29727692 33961781

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Protein kintoun

Functional Category

L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
axonemal dynein complex assembly
epithelial cilium movement involved in extracellular fluid movement

Displaying **all 3** entries
InterPro
Kintoun
PIH1, N-terminal
PIH1D1/2/3, CS-like domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110612	primary ciliary dyskinesia 10	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 57 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	35730		FB:FBgn0033224
Mus musculus	109065		MGI:1923566	MOUSE08318
Rattus norvegicus	362746		RGD:1310311	RATNO35878
Pan troglodytes	452887	9598_0:003bae		PANTR08688
Bos taurus	534465			BOVIN01118
Danio rerio	606664		ZFIN:ZDB-GENE-050809-128
Macaca mulatta	719026			MACMU42611
Xenopus tropicalis	779929		Xenbase:XB-GENE-5887533
Monodelphis domestica	100028942			MONDO02356
Xenopus laevis	100158322		Xenbase:XB-GENE-5887592

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements