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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

mitochondrial rRNA methyltransferase 3

Summary

Gene Symbol

MRM3

Organism

Homo sapiens (human)

External Links

NCBI Gene

55178

PubChem

55178

Alliance of Genome Resources

HGNC:18485

JoGo

MRM3

TogoVar

MRM3

Annotation

Keyword

3D-structure
Methyltransferase
Mitochondrion
Proteomics identification
Reference proteome
S-adenosyl-L-methionine
Transit peptide
rRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9HC36	16S rRNA (guanosine(1370)-2'-O)-methyltransferase 16S rRNA [Gm1370] 2'-O-methyltransferase RNA methyltransferase-like protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
rRNA 2'-O-methylation	TAS
rRNA processing	IMP	35177605

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

ncRNA processing [inference]

rRNA processing

rRNA modification [inference]

rRNA methylation [inference]

rRNA 2'-O-methylation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
mitochondrion	IDA
mitochondrion	HTP	34800366
mitochondrial matrix	TAS
mitochondrial matrix	IMP	35177605

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 5** entries
GO Term	Evidence Code	PMID
RNA binding	HDA	22658674 22681889
protein binding	IPI	25416956 32296183 32838362 34029587 34232536 36217030
identical protein binding	IPI	32296183
rRNA (guanosine-2'-O-)-methyltransferase activity	EXP	24036117 25074936
rRNA (guanosine-2'-O-)-methyltransferase activity	IMP	35177605

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

O-methyltransferase activity [inference]

RNA 2'-O-methyltransferase activity [inference]

rRNA (guanosine-2'-O-)-methyltransferase activity

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity [inference]

rRNA (guanosine-2'-O-)-methyltransferase activity

RNA 2'-O-methyltransferase activity [inference]

rRNA (guanosine-2'-O-)-methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity [inference]

rRNA (guanosine-2'-O-)-methyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity [inference]

rRNA (guanosine-2'-O-)-methyltransferase activity

RNA 2'-O-methyltransferase activity [inference]

rRNA (guanosine-2'-O-)-methyltransferase activity

catalytic activity, acting on a rRNA [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity [inference]

rRNA (guanosine-2'-O-)-methyltransferase activity

binding [inference]

protein binding

identical protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rRNA methyltransferase 3, mitochondrial

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
P: Inorganic ion transport and metabolism

Displaying **all 2** entries
Gene Ontology
RNA methyltransferase activity
methylation

Displaying **all 5** entries
InterPro
Alpha/beta knot methyltransferases
RNA 2-O ribose methyltransferase, substrate binding
Ribosomal protein eL30-like superfamily
tRNA (guanine-N1-)-methyltransferase, N-terminal
tRNA/rRNA methyltransferase, SpoU type

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026