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Guidelines

MIRAGE

regulation of nuclear pre-mRNA domain containing 1A

Summary

Gene Symbol

RPRD1A

Organism

Homo sapiens (human)

External Links

NCBI Gene

55197

PubChem

55197

Alliance of Genome Resources

HGNC:25560

JoGo

RPRD1A

TogoVar

RPRD1A

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Coiled coil
Direct protein sequencing
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0C4DGQ6
Q96P16	Cyclin-dependent kinase inhibitor 2B-related protein p15INK4B-related protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
RNA polymerase II promoter clearance	IMP	22231121
mRNA 3'-end processing	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

promoter clearance during DNA-templated transcription [inference]

RNA polymerase II promoter clearance

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	IDA	22231121
nucleoplasm	TAS
transcription preinitiation complex	IDA	22231121

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

transcription preinitiation complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
RNA polymerase II complex binding	IBA
protein binding	IPI	24981860 24997600 25416956 28514442 32296183 33961781
identical protein binding	IPI	24997600
RNA polymerase II C-terminal domain binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

basal transcription machinery binding [inference]

basal RNA polymerase II transcription machinery binding [inference]

RNA polymerase II complex binding

RNA polymerase II C-terminal domain binding

enzyme binding [inference]

RNA polymerase binding [inference]

RNA polymerase core enzyme binding [inference]

RNA polymerase II complex binding

RNA polymerase II C-terminal domain binding

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

regulation of nuclear pre-mrna

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
RNA polymerase II complex binding
mRNA 3'-end processing

Displaying **all 2** entries
InterPro
CID domain
ENTH/VHS

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026