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tRNA-yW synthesizing protein 1 homolog

Summary

Gene Symbol

TYW1

Organism

Homo sapiens (human)

External Links

NCBI Gene

55253

PubChem

55253

Alliance of Genome Resources

HGNC:25598

JoGo

TYW1

TogoVar

TYW1

Annotation

Keyword

4Fe-4S
Alternative splicing
Lyase
Nucleotide-binding
Proteomics identification
Reference proteome
S-adenosyl-L-methionine
tRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NV66	Radical S-adenosyl methionine and flavodoxin domain-containing protein 1 tRNA wybutosine-synthesizing protein 1 homolog tRNA-yW-synthesizing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
wybutosine biosynthetic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

organonitrogen compound metabolic process [inference]

wybutosine metabolic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

glycosyl compound metabolic process [inference]

wybutosine metabolic process [inference]

wybutosine biosynthetic process

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

organonitrogen compound metabolic process [inference]

wybutosine metabolic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

wybutosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

wybutosine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

RNA modification [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

wybutosine biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
FMN binding	IEA
metal ion binding	IEA
4 iron, 4 sulfur cluster binding	IEA
tRNA-4-demethylwyosine synthase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

oxo-acid-lyase activity [inference]

tRNA-4-demethylwyosine synthase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

tRNA-4-demethylwyosine synthase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

ribonucleotide binding [inference]

FMN binding

ion binding [inference]

anion binding [inference]

FMN binding

cation binding [inference]

metal ion binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

ribonucleotide binding [inference]

FMN binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

FMN binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 9** entries
Gene Ontology
4 iron, 4 sulfur cluster binding
FMN binding
catalytic activity
iron-sulfur cluster binding
lyase activity
metal ion binding
tRNA processing
tRNA-4-demethylwyosine synthase activity
wybutosine biosynthetic process

Displaying **all 6** entries
InterPro
Aldolase-type TIM barrel
Flavodoxin/nitric oxide synthase
Flavoprotein-like superfamily
Radical SAM
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
tRNA wybutosine-synthesis