protein phosphatase 3 catalytic subunit alpha

Summary
Gene Symbol
  • PPP3CA
Organism
Homo sapiens (human)
NCBI Gene
5530
PubChem
5530
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Calmodulin-binding
  • Cell membrane
  • Cell projection
  • Craniosynostosis
  • Cytoplasm
  • Disease variant
  • Dwarfism
  • Epilepsy
  • Hydrolase
  • Intellectual disability
  • Iron
  • Metal-binding
  • Nitration
  • Phosphoprotein
  • Protein phosphatase
  • Reference proteome
  • Synapse
  • Zinc
Proteins
Displaying all 3 entries
UniProt Protein Name
A0A0S2Z4B5
Q08209
  • CAM-PRP catalytic subunit
  • Calcineurin A alpha
  • Calmodulin-dependent calcineurin A subunit alpha isoform
  • Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
A0A0S2Z4C6
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Phosphatase
Functional Category
  • E: Amino acid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 7 entries
DO ID Disease Name Source
DOID:0050700 cardiomyopathy
DOID:0080472 developmental and epileptic encephalopathy 91
DOID:12930 dilated cardiomyopathy
DOID:1312 focal segmental glomerulosclerosis
DOID:4947 cholangiocarcinoma
DOID:5419 schizophrenia
DOID:557 kidney disease

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024