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UDP-glucose ceramide glucosyltransferase

Summary

Gene Symbol

ugcg

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

553944

KEGG Gene ID

dre:553944

PubChem

553944

Alliance of Genome Resources

ZFIN:ZDB-GENE-030131-9885

Annotation

Keyword

Glycosyltransferase
Reference proteome
Sphingolipid metabolism
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q501W7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glucosylceramide biosynthetic process	IBA
lipid metabolic process	IEA
sphingolipid metabolic process	IEA
glycosphingolipid metabolic process	IMP	16140251

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid metabolic process

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

primary metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid metabolic process

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid metabolic process

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid metabolic process

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid metabolic process

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide biosynthetic process

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

ceramide biosynthetic process [inference]

glycosylceramide biosynthetic process [inference]

glucosylceramide biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IBA IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA
transferase activity	IEA
ceramide glucosyltransferase activity	IBA IEA IMP	16140251
dihydroceramide glucosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

ceramide glucosyltransferase activity

hexosyltransferase activity [inference]

glucosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

ceramide glucosyltransferase activity

dihydroceramide glucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00720

Name

ceramide glucosyltransferase [EC:2.4.1.80]

References

8643456

Rhea

an N-acylsphing-4-enine + UDP-α-D-glucose

H⁺ + a β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + UDP

Enzyme

2.4.1.80

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10763	hypertension	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP011997
Gene Name: UDP-glucose ceramide glucosyltransferase

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	174001	WB:WBGene00019127
Caenorhabditis elegans	181790	WB:WBGene00017625
Caenorhabditis elegans	188169	WB:WBGene00011517
Drosophila melanogaster	37516	FB:FBgn0067102
Xenopus tropicalis	548887	Xenbase:XB-GENE-944694
Homo sapiens	7357	HGNC:12524
Mus musculus	22234	MGI:1332243
Rattus norvegicus	83626	RGD:621870

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024