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macroH2A.2 histone

Summary

Gene Symbol

MACROH2A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

55506

PubChem

55506

Alliance of Genome Resources

HGNC:14453

JoGo

MACROH2A2

TogoVar

MACROH2A2

Annotation

Keyword

3D-structure
Chromatin regulator
Isopeptide bond
Nucleosome core
Nucleus
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9P0M6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	IMP	19734898
negative regulation of transcription by RNA polymerase II	IBA
nucleosome assembly	IEA
brain development	IMP	19734898
sex-chromosome dosage compensation	IDA	11331621

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

protein localization to chromatin [inference]

establishment of protein localization to chromatin

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

nucleosome organization [inference]

nucleosome assembly

epigenetic regulation of gene expression [inference]

sex-chromosome dosage compensation

negative regulation of gene expression, epigenetic

heterochromatin formation

heterochromatin organization [inference]

heterochromatin formation

protein-DNA complex assembly [inference]

nucleosome assembly

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

protein localization to chromatin [inference]

establishment of protein localization to chromatin

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

establishment of localization [inference]

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

protein localization to chromatin [inference]

establishment of protein localization to chromatin

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to chromatin

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

epigenetic regulation of gene expression [inference]

sex-chromosome dosage compensation

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

epigenetic regulation of gene expression [inference]

sex-chromosome dosage compensation

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

epigenetic regulation of gene expression [inference]

sex-chromosome dosage compensation

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of epidermis development [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of multicellular organismal process [inference]

positive regulation of keratinocyte differentiation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of epidermis development [inference]

regulation of epidermal cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of epidermis development [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of epidermis development [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

epigenetic regulation of gene expression [inference]

sex-chromosome dosage compensation

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of transcription by RNA polymerase I [inference]

negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of keratinocyte differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of epidermal cell differentiation [inference]

positive regulation of epidermal cell differentiation [inference]

positive regulation of keratinocyte differentiation

regulation of keratinocyte differentiation [inference]

positive regulation of keratinocyte differentiation

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
chromosome, telomeric region	HDA	19135898
chromatin	IDA	19734898
nucleosome	IBA
Barr body	IDA	11331621
nucleus	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome [inference]

Barr body

sex chromosome [inference]

X chromosome [inference]

Barr body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome [inference]

Barr body

sex chromosome [inference]

X chromosome [inference]

Barr body

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
transcription cis-regulatory region binding	IDA	19734898
RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	23595991
protein binding	IPI	22046132 32296183
structural constituent of chromatin	IBA
chromatin DNA binding	IDA	19734898

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of chromatin

binding [inference]

protein binding

protein dimerization activity [inference]

protein heterodimerization activity

protein-containing complex binding [inference]

chromatin binding [inference]

chromatin DNA binding

nucleosomal DNA binding

nucleosome binding [inference]

nucleosomal DNA binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding

RNA polymerase II transcription regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding

RNA polymerase II transcription regulatory region sequence-specific DNA binding

chromatin DNA binding

nucleosomal DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding

RNA polymerase II transcription regulatory region sequence-specific DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Core histone macro-H2A

Functional Category

E: Amino acid transport and metabolism
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
nucleosome assembly
protein heterodimerization activity
structural constituent of chromatin

Displaying **all 8** entries
InterPro
Core histone macro-H2A, macro domain
Core histone macro-H2A
Histone H2A, C-terminal domain
Histone H2A/H2B/H3
Histone H2A
Histone-fold
Macro domain-like
Macro domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements