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dynein axonemal heavy chain 3

Summary

Gene Symbol

DNAH3

Organism

Homo sapiens (human)

External Links

NCBI Gene

55567

PubChem

55567

Alliance of Genome Resources

HGNC:2949

JoGo

DNAH3

TogoVar

DNAH3

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cilium
Coiled coil
Cytoskeleton
Dynein
Flagellum
Microtubule
Motor protein
Proteomics identification
Reference proteome
Spermatogenesis

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8V8TLI9	Axonemal beta dynein heavy chain 3 Ciliary dynein heavy chain 3
B4E1S1
Q8TD57	Axonemal beta dynein heavy chain 3 Ciliary dynein heavy chain 3 Dnahc3-b

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cilium-dependent cell motility	NAS	9256245
cilium movement involved in cell motility	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility

Displaying **all 5** entries
GO Term	Evidence Code	PMID
axonemal dynein complex	NAS	9256245
microtubule	IEA
dynein complex
inner dynein arm	IBA
9+2 motile cilium	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex

axonemal dynein complex

inner dynein arm

catalytic complex [inference]

dynein complex

axonemal dynein complex

inner dynein arm

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
microtubule motor activity	NAS	9256245
ATP binding	IEA
minus-end-directed microtubule motor activity	IBA
ATP hydrolysis activity	IEA
dynein intermediate chain binding	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

minus-end-directed microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

minus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Axonemal dynein heavy chain

Functional Category

J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
dynein intermediate chain binding
dynein light intermediate chain binding
microtubule-based movement
minus-end-directed microtubule motor activity
nucleotide binding

Displaying entries **1 - 10** of 17 in total

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InterPro
Dynein heavy chain 3, AAA+ lid domain
Dynein heavy chain AAA lid domain superfamily
Dynein heavy chain AAA lid domain
Dynein heavy chain region D6 P-loop domain
Dynein heavy chain, AAA 5 extension domain
Dynein heavy chain, AAA module D4
Dynein heavy chain, AAA1 domain, small subdomain
Dynein heavy chain, ATP-binding dynein motor region
Dynein heavy chain, C-terminal domain, barrel region
Dynein heavy chain, C-terminal domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements