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nucleoporin 133

Summary

Gene Symbol

NUP133

Organism

Homo sapiens (human)

External Links

NCBI Gene

55746

PubChem

55746

Alliance of Genome Resources

HGNC:18016

Annotation

Keyword

3D-structure
Acetylation
Centromere
Chromosome
Disease variant
Epilepsy
Intellectual disability
Kinetochore
Methylation
Nuclear pore complex
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8WUM0	133 kDa nucleoporin Nucleoporin Nup133

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
nephron development	IMP	30179222

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization

chromosome organization [inference]

transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery

protein-containing complex organization [inference]

nuclear pore organization

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

mesoderm development [inference]

paraxial mesoderm development

epithelium development [inference]

mesenchyme development [inference]

paraxial mesoderm development

tube development [inference]

neural tube development

nephron development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nuclear membrane	IDA
membrane	HDA	19946888
nuclear pore	IDA NAS	11564755 11684705 17098863 24315095
nuclear envelope	IDA TAS	24315095
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

cytosol

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11564755 15146057 17363900 24315095 24725412 24947832 26411495 26496610 27194810 30179222 31046837 33961781 35271311
structural constituent of nuclear pore	IBA IDA	11684705

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nuclear pore

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
poly(A)+ mRNA export from nucleus
protein import into nucleus
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery

Displaying **all 4** entries
InterPro
Nuclear pore complex protein Nup133-like
Nucleoporin, Nup133/Nup155-like, C-terminal
Nucleoporin, Nup133/Nup155-like, N-terminal
WD40/YVTN repeat-like-containing domain superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0060364	Galloway-Mowat syndrome 1	Alliance of Genome Resources
DOID:0080393	nephrotic syndrome type 18	Alliance of Genome Resources
DOID:0080694	Galloway-Mowat syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **81 - 90** of 90 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Salmo trutta	115208712			SALTR35928
Gadus morhua	115540428			GADMO42274
Sparus aurata	115581355			SPAAU54267
Strigops habroptila	115613727			STRHB13567
Corvus moneduloides	116440944			CORMO18595
Chelonoidis abingdonii	116826833			CHEAB26890
Rhinolophus ferrumequinum	117018547			RHIFE03425
Balaenoptera musculus	118882881			BALMU15762
Panthera leo	122202214			PANLE03642
Pongo pygmaeus	129010728	9600_0:000720

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Last updated: December 9, 2024