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nectin1b nectin cell adhesion molecule 1b [ Danio rerio (zebrafish) ]

Gene ID: 557665, updated on 21-Dec-2024

Summary

Official Symbol
nectin1bprovided by ZNC
Official Full Name
nectin cell adhesion molecule 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090224-2
See related
AllianceGenome:ZFIN:ZDB-GENE-090224-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
pvrl1b
Summary
Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and protein localization to cell junction. Predicted to be located in plasma membrane. Predicted to be active in adherens junction. Is expressed in nervous system and palatoquadrate cartilage. Human ortholog(s) of this gene implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia. Orthologous to human NECTIN1 (nectin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

See nectin1b in Genome Data Viewer
Location:
chromosome: 18
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (42924591..43226503)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (42925687..43227599)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene F-box only protein 40 Neighboring gene tetratricopeptide repeat domain 36 Neighboring gene uncharacterized LOC101885924 Neighboring gene uncharacterized LOC137488332

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
is_active_in adherens junction  
located_in membrane  
located_in plasma membrane  

General protein information

Preferred Names
nectin 1b
Names
nectin 1
nectin-1b
poliovirus receptor-related 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167569.1 → NP_001161041.1  nectin 1b precursor

    See identical proteins and their annotated locations for NP_001161041.1

    Status: PROVISIONAL

    Source sequence(s)
    AY881624
    UniProtKB/Swiss-Prot
    B0JYH6
    Conserved Domains (3) summary
    smart00408
    Location:304 → 363
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:70 → 183
    IG_like; Immunoglobulin like
    cl11960
    Location:187 → 283
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    42924591..43226503
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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