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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
desmoglein 2, tandem duplicate 1
Summary
- Gene Symbol
-
- dsg2.1
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
-
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| H2EQR6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| epiboly involved in gastrulation with mouth forming second | ||
| desmosome assembly | ||
| homophilic cell adhesion via plasma membrane adhesion molecules | ||
| convergent extension involved in gastrulation | ||
| cell adhesion |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| anchoring junction | ||
| desmosome | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| calcium ion binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Desmoglein-1
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| calcium ion binding |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| InterPro |
|---|
| Cadherin conserved site |
| Cadherin-like superfamily |
| Cadherin-like |
| Catenin binding domain superfamily |
| Desmosomal cadherin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050431 | arrhythmogenic right ventricular cardiomyopathy | |
| DOID:0110081 | arrhythmogenic right ventricular dysplasia 10 | |
| DOID:0110458 | dilated cardiomyopathy 1BB | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:9538 | multiple myeloma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1829 | HGNC:3049 | |||
| 101064287 | 31033_0:0050b9 | |||
| 101156641 | 8090_0:000ca2 | |||
| 101165259 | 8090_0:004028 | |||
| 102078996 | 8128_0:0063b7 | |||
| 102081358 | 8128_0:004c21 | |||
| 102083034 | 8128_0:0049b2 | |||
| 102083127 | 8128_0:00488b | |||
| 102083206 | 8128_0:0049d5 | |||
| 102219781 | 8083_0:002208 |
