mitogen-activated protein kinase kinase 2
| GO Term | Evidence Code | PMID |
|---|---|---|
| MAPK cascade | ||
| JNK cascade | ||
| heart development | ||
| positive regulation of gene expression | ||
| Schwann cell development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| nucleus | ||
| mitochondrion | ||
| early endosome | ||
| late endosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein serine/threonine kinase activity | ||
| MAP kinase kinase activity | ||
| MAP kinase kinase activity | ||
| protein serine/threonine/tyrosine kinase activity | ||
| protein tyrosine kinase activity |
| Gene Ontology |
|---|
| ATP binding |
| MAP kinase kinase activity |
| kinase activity |
| nucleotide binding |
| phosphorylation |
| transferase activity |
| InterPro |
|---|
| Protein kinase domain |
| Protein kinase, ATP binding site |
| Protein kinase-like domain superfamily |
| Serine/threonine-protein kinase, active site |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111463 | cardiofaciocutaneous syndrome 4 | |
| DOID:4906 | small intestine adenocarcinoma |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025