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prolactin
Summary
- Gene Symbol
-
- PRL
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of endothelial cell proliferation | ||
| cell surface receptor signaling pathway | ||
| female pregnancy | ||
| lactation | ||
| positive regulation of cell population proliferation |
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| endosome lumen |
| GO Term | Evidence Code | PMID |
|---|---|---|
| prolactin receptor binding | ||
| hormone activity | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Prolactin
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hormone activity |
| positive regulation of cell population proliferation |
| positive regulation of lactation |
| prolactin receptor binding |
| response to nutrient levels |
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Somatotropin hormone, conserved site |
| Somatotropin/prolactin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10937 | impulse control disorder | |
| DOID:3407 | carotid artery disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5617 | Xenbase:XB-GENE-482866 | ||
| 18775 | MOUSE10709 | ||
| 18776 | MOUSE10733 | ||
| 18811 | Xenbase:XB-GENE-482866 | ||
| 18812 | Xenbase:XB-GENE-482866 | ||
| 19109 | MOUSE10707 | ||
| 19110 | Xenbase:XB-GENE-482866 | ||
| 19111 | Xenbase:XB-GENE-482866 | ||
| 19114 | Xenbase:XB-GENE-482866 | ||
| 24282 | ZFIN:ZDB-GENE-030513-1 | RATNO12318 |
