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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
prolactin
Summary
- Gene Symbol
-
- PRL
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation |
|
|
| prolactin signaling pathway | ||
| positive regulation of miRNA transcription | ||
| positive regulation of lactation | ||
| lactation |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| endosome lumen | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| prolactin receptor binding | ||
| hormone activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- prolactin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hormone activity |
| positive regulation of cell population proliferation |
| positive regulation of lactation |
| prolactin receptor binding |
| response to nutrient levels |
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Somatotropin hormone, conserved site |
| Somatotropin/prolactin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:0060001 | withdrawal disorder | |
| DOID:10762 | portal hypertension | |
| DOID:10937 | impulse control disorder | |
| DOID:12700 | hyperprolactinemia | |
| DOID:1591 | renovascular hypertension | |
| DOID:1596 | depressive disorder | |
| DOID:2945 | severe acute respiratory syndrome | |
| DOID:3407 | carotid artery disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 18775 | MOUSE10709 | |||
| 18776 | MOUSE10733 | |||
| 19109 | MGI:97762 | MOUSE10707 | ||
| 24282 | RATNO12318 | |||
| 24283 | RATNO12246 | |||
| 24683 | RGD:3403 | RATNO12213 | ||
| 53950 | RATNO12472 | |||
| 66392 | MOUSE10753 | |||
| 192224 | RATNO12286 | |||
| 215028 | MOUSE10711 |
