GlyCosmos Portal

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GO Term	Evidence Code	PMID
minus-end-directed microtubule motor activity	IBA
dynein intermediate chain binding	IBA
ATP hydrolysis activity	IEA
dynein light intermediate chain binding	IBA
ATP binding	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

minus-end-directed microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

minus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

heavy chain of dynein

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
dynein intermediate chain binding
dynein light intermediate chain binding
microtubule-based movement
minus-end-directed microtubule motor activity

Displaying entries **1 - 10** of 15 in total

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InterPro
Dynein heavy chain 3, AAA+ lid domain
Dynein heavy chain AAA lid domain superfamily
Dynein heavy chain AAA lid domain
Dynein heavy chain region D6 P-loop domain
Dynein heavy chain, AAA 5 extension domain
Dynein heavy chain, AAA module D4
Dynein heavy chain, AAA1 domain, small subdomain
Dynein heavy chain, ATP-binding dynein motor region
Dynein heavy chain, C-terminal domain
Dynein heavy chain, coiled coil stalk

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9562	primary ciliary dyskinesia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	35061		FB:FBgn0013810
Mus musculus	227058		MGI:2684953	MOUSE27460
Rattus norvegicus	252893		RGD:621798	RATNO42441
Pan troglodytes	459842	9598_0:000dc8		PANTR29409
Canis lupus familiaris	488452			CANLF14074
Bos taurus	517781			BOVIN24483
Danio rerio	561639		ZFIN:ZDB-GENE-070912-282	DANRE44282
Mus musculus	627872		MGI:2685838	MOUSE28052
Macaca mulatta	695393			MACMU06610
Monodelphis domestica	100029525			MONDO22820

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements