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alpha-2-glycoprotein 1, zinc-binding

Summary

Gene Symbol

AZGP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

563

PubChem

563

Alliance of Genome Resources

HGNC:910

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
Pyrrolidone carboxylic acid
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P25311
A0A140VK00

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein transmembrane transport	IEA
detection of chemical stimulus involved in sensory perception of bitter taste	IDA	24248522
negative regulation of cell population proliferation	NAS	10462714
immune response	IBA
cell adhesion	IDA	9813179

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

cell adhesion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

transmembrane transport [inference]

protein transmembrane transport

response to stimulus [inference]

immune response

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of bitter taste

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of bitter taste

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

protein transmembrane transport

organic substance transport [inference]

protein transport [inference]

protein transmembrane transport

nitrogen compound transport [inference]

protein transport [inference]

protein transmembrane transport

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
external side of plasma membrane	IBA
collagen-containing extracellular matrix	HDA	27559042
extracellular region	HDA NAS TAS	14718574 27068509
extracellular space	HDA IBA IDA	16502470 22664934 23580065 24248522
nucleus	HDA	21630459

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16237761 18930737 28671123 32296183
protein transmembrane transporter activity	NAS	6896906
RNA nuclease activity	NAS	10462714

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

RNA nuclease activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity

transporter activity [inference]

transmembrane transporter activity [inference]

macromolecule transmembrane transporter activity [inference]

protein transmembrane transporter activity

protein transporter activity [inference]

protein transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

H-2 class I histocompatibility antigen, alpha chain-like

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
immune response

Displaying **all 7** entries
InterPro
Immunoglobulin C1-set
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
MHC class I-like antigen recognition-like superfamily
MHC class I-like antigen recognition-like
MHC classes I/II-like antigen recognition protein

Disease

Disease Ontology

Displaying entries **1 - 10** of 18 in total

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DO ID	Disease Name	Source
DOID:0050866	oral squamous cell carcinoma	Alliance of Genome Resources
DOID:0080208	metabolic dysfunction-associated steatotic liver disease	Alliance of Genome Resources
DOID:0080547	metabolic dysfunction-associated steatohepatitis	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10286	prostate carcinoma	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources
DOID:219	colon cancer	Alliance of Genome Resources
DOID:3021	acute kidney failure	Alliance of Genome Resources
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources
DOID:3748	esophagus squamous cell carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 47 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	12007		MGI:103163	MOUSE46767
Rattus norvegicus	25294		RGD:2187	RATNO04949
Canis lupus familiaris	479739			CANLF16235
Bos taurus	508800			BOVIN20912
Danio rerio	550603		ZFIN:ZDB-GENE-050417-464
Danio rerio	571647		ZFIN:ZDB-GENE-130206-11
Macaca mulatta	710136			MACMU32413
Pan troglodytes	737709	9598_0:0020b7		PANTR40907
Equus caballus	100067197			HORSE06482
Danio rerio	100149810		ZFIN:ZDB-GENE-140820-5

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements