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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
serine protease 8
Summary
- Gene Symbol
-
- PRSS8
- Aliases
-
- CAP1
- channel-activating serine protease 1
- prostasin
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q16651 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| positive regulation of sodium ion transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| plasma membrane | ||
| extracellular space | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity | ||
| protein binding | ||
| serine-type peptidase activity |
|
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050789 | tarsal-carpal coalition syndrome | |
| DOID:0060180 | colitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis | |
| DOID:0060713 | autosomal recessive congenital ichthyosis 4B | |
| DOID:10155 | intestinal cancer | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10763 | hypertension | |
| DOID:10825 | essential hypertension |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 436869 | ZFIN:ZDB-GENE-040718-339 | ||
| 100001520 | ZFIN:ZDB-GENE-141212-262 | ||
| 398015 | Xenbase:XB-GENE-6252055 | ||
| 549734 | Xenbase:XB-GENE-5758112 | ||
| 113449984 | PSETE23864 | ||
| 100077713 | ORNAN16737 | ||
| 103119747 | ERIEU08951 | ||
| 100387658 | CALJA06104 | ||
| 105599531 | CERAT36649 | ||
| 713176 | MACMU27246 |
