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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
serine protease 8
Summary
- Gene Symbol
-
- PRSS8
- Aliases
-
- CAP1
- channel-activating serine protease 1
- prostasin
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q16651 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| positive regulation of sodium ion transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| plasma membrane | ||
| extracellular space | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity | ||
| protein binding | ||
| serine-type peptidase activity |
|
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4006 | bladder urothelial carcinoma | |
| DOID:4007 | bladder carcinoma | |
| DOID:445 | Bartter disease | |
| DOID:4450 | renal cell carcinoma | |
| DOID:4451 | renal carcinoma | |
| DOID:446 | primary hyperaldosteronism | |
| DOID:4464 | collecting duct carcinoma | |
| DOID:4465 | papillary renal cell carcinoma | |
| DOID:4467 | clear cell renal cell carcinoma | |
| DOID:4471 | chromophobe renal cell carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101082616 | FELCA35152 | ||
| 122209713 | PANLE07441 | ||
| 118880605 | BALMU21531 | ||
| 102148278 | HORSE07069 | ||
| 100522730 | PIGXX20576 | ||
| 613506 | BOVIN20647 | ||
| 102179341 | CAPHI17068 | ||
| 105982095 | DIPOR07941 | ||
| 76560 | MGI:1923810 | MOUSE53523 | |
| 192107 | RGD:619973 | RATNO17495 |
