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Guidelines

MIRAGE

deoxyribonuclease II beta

Summary

Gene Symbol

Dnase2b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56629

PubChem

56629

Alliance of Genome Resources

MGI:1913283

Annotation

Keyword

Endonuclease
Glycoprotein
Lysosome
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QY48	DNase II-like acid DNase DNase2-like acid DNase Deoxyribonuclease II beta Endonuclease DLAD

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
DNA metabolic process	IEA
apoptotic DNA fragmentation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	IDA	10497274
cytoplasm	IDA	10497274
lysosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
DNA endonuclease activity	IDA	10497274
endodeoxyribonuclease activity	IDA	10497274
deoxyribonuclease II activity	ISO
deoxyribonuclease II activity	IBA
deoxyribonuclease II activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

endodeoxyribonuclease activity

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [inference]

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

DNA nuclease activity [inference]

endodeoxyribonuclease activity

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

endodeoxyribonuclease activity

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Deoxyribonuclease-2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
deoxyribonuclease II activity
hydrolase activity

Displaying 1 entry
InterPro
Deoxyribonuclease II

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:83	cataract	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 92 in total

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Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	1777	FB:FBgn0000477
Drosophila melanogaster	13423	FB:FBgn0000477
Xenopus tropicalis	56629	Xenbase:XB-GENE-980313
Homo sapiens	58511	Xenbase:XB-GENE-980313	HUMAN50577
Rattus norvegicus	59296	Xenbase:XB-GENE-980313	RATNO23328
Drosophila melanogaster	171575	FB:FBgn0000477
Xenopus tropicalis	176166	Xenbase:XB-GENE-980313
Xenopus tropicalis	176316	Xenbase:XB-GENE-980313
Xenopus tropicalis	181174	Xenbase:XB-GENE-980313
Pan troglodytes	469369		PANTR21482

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: December 8, 2025