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C-C motif chemokine ligand 28

Summary

Gene Symbol

Ccl28

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56838

PubChem

56838

Alliance of Genome Resources

MGI:1861731

Annotation

Keyword

Chemotaxis
Cytokine
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JIL2	Small-inducible cytokine A28

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
killing of cells of another organism	IDA ISO	12538707
cell chemotaxis	IBA IDA IEA ISO	12538707
negative regulation of leukocyte tethering or rolling	IEA ISO
positive regulation of cell-matrix adhesion	IBA IEA ISO
immune response	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

cellular process [inference]

cell killing [inference]

killing of cells of another organism

cytolysis in another organism

signal transduction

cytolysis [inference]

cytolysis in another organism

cell motility [inference]

cell migration [inference]

cell chemotaxis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

cytolysis in another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular process [inference]

signal transduction

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
secretory granule	ISO
extracellular region
extracellular space	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

Displaying 1 entry
GO Term	Evidence Code	PMID
chemokine activity	IBA IDA ISO ISS	10781587 12538707

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

cytokine receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

C-C motif chemokine 28

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 5** entries
Gene Ontology
cell chemotaxis
chemokine activity
chemotaxis
cytokine activity
immune response

Displaying **all 2** entries
InterPro
Chemokine interleukin-8-like domain
Chemokine interleukin-8-like superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10763	hypertension	Alliance of Genome Resources
DOID:3310	atopic dermatitis	Alliance of Genome Resources
DOID:614	lymphopenia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	56477		HGNC:17700	HUMAN79050
Rattus norvegicus	114492	10116_1:000e22	RGD:619937
Canis lupus familiaris	448795			CANLF14973
Bos taurus	535328			BOVIN15975
Macaca mulatta	574221			MACMU37848
Pan troglodytes	735978			PANTR35619
Ovis aries	780500			SHEEP06957
Danio rerio	794616		ZFIN:ZDB-GENE-140714-1
Callithrix jacchus	100400116			CALJA25056
Nomascus leucogenys	100587571			NOMLE34390