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C-C motif chemokine ligand 28

Summary

Gene Symbol

Ccl28

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56838

PubChem

56838

Alliance of Genome Resources

MGI:1861731

Annotation

Keyword

Chemotaxis
Cytokine
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JIL2	Small-inducible cytokine A28

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
antimicrobial humoral immune response mediated by antimicrobial peptide	IDA ISO	12538707
positive regulation of cytosolic calcium ion concentration	IDA	10781587
signal transduction	IEA
cytolysis in another organism	ISO

GO Hierarchy

biological process

immune system process [inference]

immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

cellular process [inference]

cell killing [inference]

killing of cells of another organism

cytolysis in another organism

signal transduction

cytolysis [inference]

cytolysis in another organism

cell motility [inference]

cell migration [inference]

cell chemotaxis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

cytolysis in another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular process [inference]

signal transduction

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte adhesion to vascular endothelial cell [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of leukocyte tethering or rolling [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of leukocyte tethering or rolling

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
secretory granule	ISO
extracellular region
extracellular space	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

Displaying 1 entry
GO Term	Evidence Code	PMID
chemokine activity	IBA IDA ISO ISS	10781587 12538707

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

cytokine receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

C-C motif chemokine 28

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 5** entries
Gene Ontology
cell chemotaxis
chemokine activity
chemotaxis
cytokine activity
immune response

Displaying **all 2** entries
InterPro
Chemokine interleukin-8-like domain
Chemokine interleukin-8-like superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10763	hypertension	Alliance of Genome Resources
DOID:3310	atopic dermatitis	Alliance of Genome Resources
DOID:614	lymphopenia	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 73 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Jaculus jaculus	101617632	51337_0:004c20
Heterocephalus glaber	101711298	10181_0:001ba0
Mesocricetus auratus	101843973	10036_0:0034f0
Ictidomys tridecemlineatus	101956621	43179_0:003d1f	ICTTR01723
Microtus ochrogaster	101998042	79684_0:00260b
Chinchilla lanigera	102004434	34839_0:0024b3	CHILA12214
Macaca fascicularis	102135326		MACFA35429
Vicugna pacos	102539107		VICPA01564
Peromyscus maniculatus bairdii	102915403	230844_0:003d89
Carlito syrichta	103272121		CARSF24210