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nicalin

Summary

Gene Symbol

NCLN

Organism

Homo sapiens (human)

External Links

NCBI Gene

56926

PubChem

56926

Alliance of Genome Resources

HGNC:26923

Annotation

Keyword

3D-structure
Alternative splicing
Endoplasmic reticulum
Glycoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q969V3	Nicalin Nicastrin-like protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
determination of left/right asymmetry in lateral mesoderm	ISS
regulation of signal transduction	IBA
regulation of protein-containing complex assembly	IDA	20538592
protein stabilization	IMP	20538592
regulation of protein complex stability	IDA	20538592

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

multicellular organismal process [inference]

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry [inference]

determination of left/right asymmetry in lateral mesoderm

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

establishment of localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into ER membrane [inference]

multi-pass transmembrane protein insertion into ER membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of activin receptor signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of nodal signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of activin receptor signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of nodal signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of activin receptor signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of nodal signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of activin receptor signaling pathway [inference]

negative regulation of nodal signaling pathway

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

regulation of protein complex stability

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IDA	20538592
endoplasmic reticulum membrane	IBA
membrane	HDA	19946888
protein-containing complex	IDA	20538592
multi-pass translocon complex	IDA	36261522