GlyCosmos Portal

Annotation

Keyword

Acetylation
Alternative splicing
Golgi apparatus
Magnesium
Manganese
Metal-binding
Phospholipid biosynthesis
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8WUD6	AAPT1-like protein Diacylglycerol cholinephosphotransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
phosphatidylcholine biosynthetic process	IDA	10893425
platelet activating factor biosynthetic process	IDA	10893425
regulation of cell growth		10893425
CDP-choline pathway		10893425
lipid metabolic process		10893425

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

primary metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

small molecule metabolic process [inference]

ether metabolic process [inference]

glycerol ether metabolic process [inference]

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

ether metabolic process [inference]

glycerol ether metabolic process [inference]

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organonitrogen compound metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of cell growth

regulation of cellular process [inference]

regulation of cellular component organization [inference]

regulation of cell growth

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane		10893425
Golgi apparatus	IBA
endoplasmic reticulum membrane	IBA
intracellular membrane-bounded organelle		10893425
Golgi membrane	IDA TAS	12221122

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
diacylglycerol binding		10893425
metal ion binding	IEA
diacylglycerol cholinephosphotransferase activity	IBA IDA	10893425

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups [inference]

CDP-alcohol phosphatidyltransferase activity [inference]

diacylglycerol cholinephosphotransferase activity

binding [inference]

protein binding

lipid binding [inference]

diacylglycerol binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cholinephosphotransferase

Functional Category

I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 6** entries
Gene Ontology
diacylglycerol cholinephosphotransferase activity
ethanolaminephosphotransferase activity
phosphatidylethanolamine biosynthetic process
phospholipid biosynthetic process
phosphotransferase activity, for other substituted phosphate groups
transferase activity

Displaying **all 4** entries
InterPro
CDP-alcohol phosphatidyltransferase, conserved site
CDP-alcohol phosphatidyltransferase, transmembrane domain
CDP-alcohol phosphatidyltransferase
Choline/ethanolamine phosphotransferase

Rhea

RHEA:36179

1-O-alkyl-2-acyl-sn-glycerol + CDP-choline

H⁺ + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CMP

Enzyme

2.7.8.2

RHEA:32939

a 1,2-diacyl-sn-glycerol + CDP-choline

H⁺ + a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP

Enzyme

2.7.8.2

PMID

RHEA:36183

a 1-O-alkyl-2-acetyl-sn-glycerol + CDP-choline

H⁺ + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CMP

Enzyme

2.7.8.2

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5679	retinal disease	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006641
Gene Name: choline phosphotransferase 1

Ortholog

Displaying entries **11 - 20** of 64 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Ornithorhynchus anatinus	100075425			ORNAN06452
Xenopus tropicalis	100216268		Xenbase:XB-GENE-973251
Taeniopygia guttata	100219586			TAEGU09139
Oryctolagus cuniculus	100353669			RABIT10677
Callithrix jacchus	100401644			CALJA45781
Pongo abelii	100440613	9601_0:00336f		PONAB05957
Sus scrofa	100523738			PIGXX26662
Oreochromis niloticus	100703364			ORENI24183
Cavia porcellus	100718704			CAVPO05860
Pan paniscus	100986998	9597_0:003568

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements