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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
atypical chemokine receptor 3
Summary
- Gene Symbol
-
- ACKR3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell adhesion
- Cell membrane
- Developmental protein
- Disease variant
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Glycoprotein
- Host-virus interaction
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P25106 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| vasculogenesis | ||
| positive regulation of cytosolic calcium ion concentration | ||
| positive regulation of ERK1 and ERK2 cascade | ||
| angiogenesis |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| recycling endosome | ||
| external side of plasma membrane | ||
| early endosome | ||
| intracellular membrane-bounded organelle | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| scavenger receptor activity | ||
| coreceptor activity | ||
| C-X-C chemokine binding | ||
| C-X-C chemokine receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- G-protein coupled receptor 182
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| angiogenesis |
| chemokine binding |
| chemotaxis |
| vasculogenesis |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| G-protein coupled estrogen receptor 1-like |
| GPCR, rhodopsin-like, 7TM |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100655766 | LOXAF06374 | |||
| 100703676 | ORENI19336 | |||
| 100729562 | CAVPO07822 | |||
| 100774656 | CRIGR26680 | |||
| 100919342 | SARHA07768 | |||
| 100964816 | OTOGA04850 | |||
| 100980618 | 9597_0:000e20 | PANPA26961 | ||
| 101019094 | PAPAN01819 | |||
| 101030558 | SAIBB27299 | |||
| 101080817 | FELCA18690 |
