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nucleoporin 107

Summary

Gene Symbol

NUP107

Organism

Homo sapiens (human)

External Links

NCBI Gene

57122

PubChem

57122

Alliance of Genome Resources

HGNC:29914

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Centromere
Chromosome
Disease variant
Epilepsy
Intellectual disability
Kinetochore
Membrane
Methylation
Nuclear pore complex
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P57740	107 kDa nucleoporin Nucleoporin Nup107

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
nephron development	IMP	30179222
female gonad development	IMP	26485283

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization [inference]

nuclear pore complex assembly

chromosome organization [inference]

transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [inference]

post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery

cellular component assembly [inference]

protein-containing complex assembly [inference]

pore complex assembly [inference]

nuclear pore complex assembly

protein-containing complex organization [inference]

nuclear pore organization [inference]

nuclear pore complex assembly

protein-containing complex assembly [inference]

pore complex assembly [inference]

nuclear pore complex assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

anatomical structure development [inference]

animal organ development [inference]

gonad development [inference]

female gonad development

reproductive structure development [inference]

gonad development [inference]

female gonad development

nephron development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nuclear membrane	IDA	12802065 15229283
membrane	HDA	19946888
nuclear pore	IDA NAS	11564755 11684705 12802065 15229283 24315095 26411495
nuclear periphery	IDA	15229283
nuclear envelope	IDA TAS	24315095

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

cytosol

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

nuclear periphery

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11564755 15146057 17363900 24407287 26411495 26496610 27194810 30179222 33961781 35271311
structural constituent of nuclear pore	IBA IDA IMP	11684705 15229283

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nuclear pore

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
mRNA export from nucleus
mRNA transport
post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
protein import into nucleus

Displaying 1 entry
InterPro
Nuclear pore protein 84/107

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080385	nephrotic syndrome type 11	Alliance of Genome Resources
DOID:0080498	ovarian dysgenesis 6	Alliance of Genome Resources
DOID:0080694	Galloway-Mowat syndrome	Alliance of Genome Resources
DOID:14450	46 XX gonadal dysgenesis	Alliance of Genome Resources

Ortholog

Displaying entries **81 - 90** of 90 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Gadus morhua	115542453			GADMO44599
Sparus aurata	115595549			SPAAU49600
Strigops habroptila	115605364			STRHB21817
Corvus moneduloides	116442797			CORMO20613
Chelonoidis abingdonii	116834444			CHEAB16515
Rhinolophus ferrumequinum	117029340			RHIFE08845
Scophthalmus maximus	118289787			SCOMX21499
Balaenoptera musculus	118902497			BALMU03981
Panthera leo	122224811			PANLE18079
Pongo pygmaeus	129009947	9600_0:003490

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Last updated: December 9, 2024