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prostaglandin E receptor 1

Summary

Gene Symbol

PTGER1

Organism

Homo sapiens (human)

External Links

NCBI Gene

5731

PubChem

5731

Alliance of Genome Resources

HGNC:9593

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P34995	Prostanoid EP1 receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
response to prostaglandin E	IDA	8253813
response to lipopolysaccharide	IEA
phospholipase C-activating G protein-coupled receptor signaling pathway		8253813
inflammatory response	IBA
positive regulation of cytosolic calcium ion concentration	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

dopamine receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to lipid [inference]

response to lipopolysaccharide

response to prostaglandin [inference]

response to prostaglandin E

response to alcohol [inference]

response to prostaglandin E

response to ketone [inference]

response to prostaglandin E

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to alcohol [inference]

response to prostaglandin E

response to ketone [inference]

response to prostaglandin E

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

dopamine receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IBA IDA TAS	8253813

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
D1 dopamine receptor binding	IEA
prostaglandin E receptor activity	IBA IDA	8253813

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

dopamine receptor binding [inference]

D1 dopamine receptor binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

prostaglandin E receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Uncharacterized protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
inflammatory response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10808	gastric ulcer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	19216	MGI:97793	MOUSE57935
Rattus norvegicus	25637	RGD:3434	RATNO14820
Drosophila melanogaster	39966	FB:FBgn0036742
Bos taurus	507437		BOVIN32428
Danio rerio	559315	ZFIN:ZDB-GENE-120215-261	DANRE38453
Danio rerio	564945	ZFIN:ZDB-GENE-100922-278	DANRE31088
Danio rerio	100003535	ZFIN:ZDB-GENE-120917-4
Monodelphis domestica	100026455		MONDO19991
Ornithorhynchus anatinus	100086373		ORNAN24956
Callithrix jacchus	100396387		CALJA24230

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements