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prostaglandin E receptor 4

Summary

Gene Symbol

PTGER4

Organism

Homo sapiens (human)

External Links

NCBI Gene

5734

PubChem

5734

Alliance of Genome Resources

HGNC:9596

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P35408	Prostanoid EP4 receptor
A0PJF5	Prostanoid EP4 receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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Last »
GO Term	Evidence Code	PMID
positive regulation of cytokine production	ISS
cellular response to mechanical stimulus	ISS
cellular response to prostaglandin E stimulus	IBA
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	16204467
JNK cascade	ISS

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

ERK1 and ERK2 cascade

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

bone development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to nematode

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

immune response

response to external stimulus [inference]

response to mechanical stimulus

cellular response to mechanical stimulus

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

response to abiotic stimulus [inference]

response to mechanical stimulus

cellular response to mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to prostaglandin [inference]

response to prostaglandin E

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to prostaglandin [inference]

response to prostaglandin E

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to lipid [inference]

response to lipopolysaccharide

response to prostaglandin [inference]

response to prostaglandin E

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to alcohol [inference]

response to prostaglandin E

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to ketone [inference]

response to prostaglandin E

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to alcohol [inference]

response to prostaglandin E

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to ketone [inference]

response to prostaglandin E

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil extravasation [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil migration [inference]

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil extravasation [inference]

negative regulation of eosinophil extravasation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil extravasation [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil migration [inference]

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular component organization [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of integrin activation

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

regulation of inflammatory response [inference]

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

positive regulation of defense response [inference]

positive regulation of inflammatory response

regulation of inflammatory response [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

ERK1 and ERK2 cascade

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

regulation of stress fiber assembly

regulation of cellular component biogenesis [inference]

regulation of actin filament bundle assembly [inference]

regulation of stress fiber assembly

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of integrin activation

regulation of integrin activation [inference]

negative regulation of integrin activation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular component organization [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of integrin activation

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

regulation of stress fiber assembly

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of integrin activation

regulation of integrin activation [inference]

negative regulation of integrin activation

negative regulation of cellular component organization [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of integrin activation

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

regulation of stress fiber assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of cellular extravasation [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil extravasation [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil migration [inference]

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of eosinophil extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of cellular extravasation [inference]

negative regulation of eosinophil extravasation

negative regulation of eosinophil migration [inference]

negative regulation of eosinophil extravasation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

regulation of ossification

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	NAS	8163486
plasma membrane	IBA IDA TAS	16424369 8163486

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16424369
prostaglandin E receptor activity	IBA IDA	8078484 8163486

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

prostaglandin E receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Uncharacterized protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
inflammatory response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor

Disease

Disease Ontology

Displaying entries **1 - 10** of 12 in total

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2

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DO ID	Disease Name	Source
DOID:11476	osteoporosis	Alliance of Genome Resources
DOID:12510	retinal ischemia	Alliance of Genome Resources
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:1679	cystitis	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:2349	arteriosclerosis	Alliance of Genome Resources
DOID:3021	acute kidney failure	Alliance of Genome Resources
DOID:3627	aortic aneurysm	Alliance of Genome Resources
DOID:7147	ankylosing spondylitis	Alliance of Genome Resources
DOID:783	end stage renal disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	19219		MGI:104311	MOUSE15050
Drosophila melanogaster	39966		FB:FBgn0036742
Rattus norvegicus	84023		RGD:628641	RATNO22958
Bos taurus	282331			BOVIN16012
Canis lupus familiaris	403589			CANLF14992
Pan troglodytes	450195	9598_0:001960		PANTR35662
Danio rerio	560057		ZFIN:ZDB-GENE-070705-128
Danio rerio	562469		ZFIN:ZDB-GENE-060222-1
Macaca mulatta	695220			MACMU39799
Danio rerio	100005416		ZFIN:ZDB-GENE-060531-102

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements