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DS cell adhesion molecule like 1

Summary

Gene Symbol

DSCAML1

Organism

Homo sapiens (human)

External Links

NCBI Gene

57453

PubChem

57453

Alliance of Genome Resources

HGNC:14656

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Neurogenesis
Proteomics identification
Reference proteome
Repeat
Signal
Synapse
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A384DVL8
Q8TD84	Down syndrome cell adhesion molecule 2 Down syndrome cell adhesion molecule-like protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
dorsal/ventral pattern formation	NAS	12051741
brain development	IDA	12051741
embryonic skeletal system morphogenesis	IDA	12051741
dendrite self-avoidance	IBA
homophilic cell adhesion via plasma membrane adhesion molecules	IBA IDA	11453658

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell recognition [inference]

neuron recognition [inference]

dendrite self-avoidance

cellular developmental process [inference]

cell fate determination

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

dorsal/ventral pattern formation

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis

skeletal system morphogenesis [inference]

embryonic skeletal system morphogenesis

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis

anatomical structure development [inference]

animal organ development [inference]

brain development

system development [inference]

central nervous system development

cellular developmental process [inference]

cell fate determination

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA TAS
cell surface	IDA	11453658
axon	IBA
extracellular space	HDA	22664934
synapse	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein homodimerization activity	IDA	11453658
cell-cell adhesion mediator activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Down syndrome cell adhesion molecule

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
cell-cell adhesion mediator activity
dendrite self-avoidance
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 2** entries
InterPro
Immunoglobulin-like domain superfamily
Immunoglobulin-like fold

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:14250	Down syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 84 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	35652		FB:FBgn0033159
Drosophila melanogaster	38788		FB:FBgn0265296
Drosophila melanogaster	42103		FB:FBgn0261046
Mus musculus	114873		MGI:2150309	MOUSE63085
Rattus norvegicus	315615		RGD:1304887	RATNO39924
Pan troglodytes	451577	9598_0:0033a2		PANTR04436
Canis lupus familiaris	489388			CANLF15247
Macaca mulatta	698212			MACMU10073
Drosophila melanogaster	2769008		FB:FBgn0263219
Taeniopygia guttata	100223481			TAEGU14084

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements