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exportin 5

Summary

Gene Symbol

XPO5

Organism

Homo sapiens (human)

External Links

NCBI Gene

57510

PubChem

57510

Alliance of Genome Resources

HGNC:17675

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Direct protein sequencing
Host-virus interaction
Nucleus
Phosphoprotein
Protein transport
RNA-mediated gene silencing
Reference proteome
tRNA-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9HAV4	Ran-binding protein 21

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
RNA export from nucleus	IBA
protein export from nucleus	IDA	11777942 24209753
miRNA metabolic process	TAS
pre-miRNA export from nucleus	NAS	19965479
pre-miRNA export from nucleus	IDA	15613540

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

ncRNA metabolic process [inference]

miRNA metabolic process

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus

pre-miRNA export from nucleus

protein export from nucleus

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus

pre-miRNA export from nucleus

protein export from nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

pre-miRNA export from nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

pre-miRNA export from nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus

pre-miRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus

pre-miRNA export from nucleus

protein export from nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus

pre-miRNA export from nucleus

protein export from nucleus

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

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GO Term	Evidence Code	PMID
nucleus	IDA	11777942
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA
cytoplasm	IDA	11777942

GO Hierarchy

cellular component

protein-containing complex [inference]

nucleocytoplasmic transport complex [inference]

RNA nuclear export complex

ribonucleoprotein complex [inference]

RNAi effector complex [inference]

RISC complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
tRNA binding	IEA
RNA binding	TAS
RNA binding	IBA
RNA binding	HDA	22658674 22681889
mRNA binding	IDA	21297638

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

RISC complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

molecular carrier activity [inference]

nucleocytoplasmic carrier activity [inference]

nuclear export signal receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Exportin

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
RNA export from nucleus

Displaying **all 5** entries
InterPro
Armadillo-like helical
Armadillo-type fold
Exportin-1/5
Exportin-1/Importin-beta-like
Exportin-5, C-terminal domain

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:5409	lung small cell carcinoma	Alliance of Genome Resources
DOID:5426	primary ovarian insufficiency	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources
DOID:9538	multiple myeloma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 86 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	57510	Xenbase:XB-GENE-5947328
Mus musculus	72322		MOUSE22369
Rattus norvegicus	363194		RATNO42365
Pan troglodytes	472014		PANTR38238
Canis lupus familiaris	474913		CANLF02783
Macaca mulatta	700664		MACMU34389
Monodelphis domestica	100011817		MONDO14145
Ornithorhynchus anatinus	100092388		ORNAN10722
Sus scrofa	100155084		PIGXX31625
Taeniopygia guttata	100224518		TAEGU21208

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements