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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
stromal interaction molecule 2
Summary
- Gene Symbol
-
- STIM2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium transport
- Coiled coil
- Direct protein sequencing
- Endoplasmic reticulum
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion transmembrane transport | ||
| intracellular calcium ion homeostasis | ||
| positive regulation of calcium ion transport | ||
| store-operated calcium entry | ||
| activation of store-operated calcium channel activity |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
positive regulation of transport [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum membrane | ||
| plasma membrane | ||
| endoplasmic reticulum |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| store-operated calcium channel activity | ||
| calcium channel regulator activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Stromal interaction molecule
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11984 | hypertrophic cardiomyopathy | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:936 | brain disease | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 32556 | FB:FBgn0045073 | |||
| 116873 | MGI:2151156 | MOUSE45828 | ||
| 117087 | RGD:1304641 | RATNO08806 | ||
| 175201 | WB:WBGene00021910 | |||
| 461155 | 9598_0:00145d | PANTR33460 | ||
| 479120 | CANLF12280 | |||
| 541299 | BOVIN31324 | |||
| 563901 | ZFIN:ZDB-GENE-120404-3 | DANRE39512 | ||
| 694980 | MACMU36812 | |||
| 733739 | Xenbase:XB-GENE-992607 |
