protein tyrosine phosphatase non-receptor type 11

Summary
Gene Symbol
  • PTPN11
Organism
Homo sapiens (human)
NCBI Gene
5781
PubChem
5781
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Deafness
  • Disease variant
  • Nucleus
  • Phosphoprotein
  • Protein phosphatase
  • Reference proteome
  • Repeat
  • SH2 domain
Proteins
Displaying 1 entry
UniProt Protein Name
Q06124
  • Protein-tyrosine phosphatase 1D
  • Protein-tyrosine phosphatase 2C
  • SH-PTP2
  • SH-PTP3
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Growth factor receptor-bound protein
Functional Category
  • E: Amino acid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying entries 1 - 10 of 19 in total
DO ID Disease Name Source
DOID:0014667 disease of metabolism
DOID:0050458 juvenile myelomonocytic leukemia
DOID:0050868 hepatocellular adenoma
DOID:0060250 idiopathic scoliosis
DOID:0060578 Noonan syndrome 1
DOID:0080548 Noonan syndrome with multiple lentigines 1
DOID:0111512 metachondromatosis
DOID:10534 stomach cancer
DOID:11168 anogenital venereal wart
DOID:11984 hypertrophic cardiomyopathy

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024