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glucose-6-phosphatase catalytic subunit 2
Summary
- Gene Symbol
-
- G6PC2
- Aliases
-
- IGRP
- islet specific glucose 6 phosphatase catalytic subunit related protein
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Endoplasmic reticulum
- Gluconeogenesis
- Glycoprotein
- Hydrolase
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9NQR9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| gluconeogenesis | ||
| glucose homeostasis | ||
| glucose 6-phosphate metabolic process | ||
| regulation of insulin secretion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| endoplasmic reticulum membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| glucose-6-phosphatase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Glucose-6-phosphatase
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| gluconeogenesis |
| glucose-6-phosphatase activity |
| hydrolase activity |
| InterPro |
|---|
| Glucose-6-phosphatase |
| Phosphatidic acid phosphatase type 2/haloperoxidase superfamily |
| Phosphatidic acid phosphatase type 2/haloperoxidase |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9744 | type 1 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14378 | MGI:1277193 | MOUSE31983 | ||
| 33476 | FB:FBgn0031463 | |||
| 505012 | BOVIN24131 | |||
| 681817 | RGD:69398 | |||
| 709062 | MACMU06017 | |||
| 741431 | 9598_0:000eb9 | PANTR29045 | ||
| 100062750 | HORSE13923 | |||
| 100083297 | ORNAN26770 | |||
| 100345755 | RABIT11745 | |||
| 100453765 | 9601_0:000e37 | PONAB24135 |
