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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
protein tyrosine phosphatase receptor type B
Summary
- Gene Symbol
-
- PTPRB
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Glycoprotein
- Phosphoprotein
- Protein phosphatase
- Proteomics identification
- Reference proteome
- Repeat
- Signal
- Transmembrane
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphate-containing compound metabolic process | ||
| dephosphorylation | ||
| glial cell migration | ||
| protein dephosphorylation | ||
| osteoblast differentiation |
| GO Term | Evidence Code | PMID |
|---|---|---|
| receptor complex | ||
| plasma membrane | ||
| tertiary granule membrane | ||
| specific granule membrane |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Receptor-type tyrosine-protein phosphatase beta
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| angiogenesis |
| cadherin binding |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Immunoglobulin-like fold |
| PTPRJ, transmembrane domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0001816 | angiosarcoma | |
| DOID:0060108 | brain glioma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:1115 | sarcoma | |
| DOID:3068 | glioblastoma | |
| DOID:3347 | osteosarcoma | |
| DOID:3498 | pancreatic ductal adenocarcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:3963 | thyroid gland carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 19263 | MGI:97809 | MOUSE01567 | ||
| 31425 | FB:FBgn0004368 | |||
| 32115 | FB:FBgn0004370 | |||
| 174437 | WB:WBGene00009717 | |||
| 314843 | RGD:1305922 | RATNO37730 | ||
| 452074 | 9598_0:0036e0 | PANTR06404 | ||
| 481162 | CANLF01422 | |||
| 505696 | BOVIN29412 | |||
| 718564 | MACMU04577 | |||
| 100015898 | MONDO34330 |
