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BCL2 associated X, apoptosis regulator

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

581

PubChem

581

Alliance of Genome Resources

HGNC:959

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Cytoplasm
Host-virus interaction
Isopeptide bond
Mitochondrion outer membrane
Nucleus
Proteomics identification
Reference proteome
Transmembrane helix
Tumor suppressor
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q5ZPJ1
I6LPK7
Q07812	Bcl-2-like protein 4
Q5ZPJ0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 90 in total

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GO Term	Evidence Code	PMID
regulation of mammary gland epithelial cell proliferation	IEA
positive regulation of apoptotic DNA fragmentation	IMP	11350920
response to toxic substance	IDA	16307838
spermatid differentiation	IEA
positive regulation of reproductive process	IEA

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

myeloid cell homeostasis

B cell selection [inference]

B cell negative selection

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

T cell proliferation [inference]

T cell homeostatic proliferation

B cell activation [inference]

B cell proliferation [inference]

B cell homeostatic proliferation

lymphocyte proliferation [inference]

T cell proliferation [inference]

T cell homeostatic proliferation

B cell proliferation [inference]

B cell homeostatic proliferation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

carbohydrate derivative metabolic process [inference]

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

T cell proliferation [inference]

T cell homeostatic proliferation

B cell activation [inference]

B cell proliferation [inference]

B cell homeostatic proliferation

lymphocyte proliferation [inference]

T cell proliferation [inference]

T cell homeostatic proliferation

B cell proliferation [inference]

B cell homeostatic proliferation

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

extrinsic apoptotic signaling pathway

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway

signal transduction in absence of ligand [inference]

extrinsic apoptotic signaling pathway in absence of ligand

apoptotic signaling pathway

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

neuron apoptotic process [inference]

motor neuron apoptotic process

leukocyte apoptotic process [inference]

lymphocyte apoptotic process [inference]

B cell apoptotic process

T cell apoptotic process [inference]

thymocyte apoptotic process

apoptotic process involved in development [inference]

apoptotic process involved in morphogenesis [inference]

epithelial cell apoptotic process

programmed cell death involved in cell development [inference]

cell population proliferation [inference]

epithelial cell proliferation [inference]

Sertoli cell proliferation

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

T cell proliferation [inference]

T cell homeostatic proliferation

B cell proliferation [inference]

B cell homeostatic proliferation

cellular process involved in reproduction in multicellular organism [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

cell differentiation [inference]

spermatid differentiation

cell development [inference]

germ cell development

cell motility [inference]

cell migration [inference]

neuron migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial membrane organization [inference]

regulation of mitochondrial membrane permeability [inference]

positive regulation of mitochondrial membrane permeability [inference]

mitochondrial outer membrane permeabilization involved in programmed cell death [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of mitochondrial membrane permeability involved in apoptotic process [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

mitochondrial fusion

apoptotic mitochondrial changes

regulation of mitochondrial membrane permeability involved in apoptotic process [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

organelle fusion [inference]

mitochondrial fusion

membrane organization [inference]

mitochondrial membrane organization [inference]

regulation of mitochondrial membrane permeability [inference]

positive regulation of mitochondrial membrane permeability [inference]

mitochondrial outer membrane permeabilization involved in programmed cell death [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of mitochondrial membrane permeability involved in apoptotic process [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

supramolecular fiber organization

execution phase of apoptosis

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

female genitalia development [inference]

vagina development

fertilization

cellular process involved in reproduction in multicellular organism [inference]

Sertoli cell proliferation

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

T cell proliferation [inference]

T cell homeostatic proliferation

B cell activation [inference]

B cell proliferation [inference]

B cell homeostatic proliferation

lymphocyte proliferation [inference]

T cell proliferation [inference]

T cell homeostatic proliferation

B cell proliferation [inference]

B cell homeostatic proliferation

tissue remodeling [inference]

blood vessel remodeling

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

female genitalia development [inference]

vagina development

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

odontogenesis [inference]

odontogenesis of dentin-containing tooth

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

post-embryonic eye morphogenesis [inference]

post-embryonic camera-type eye morphogenesis

anatomical structure development [inference]

cell development [inference]

germ cell development

animal organ development [inference]

kidney development

genitalia development [inference]

female genitalia development [inference]

vagina development

reproductive structure development [inference]

genitalia development [inference]

female genitalia development [inference]

vagina development

retina development in camera-type eye

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

cell differentiation [inference]

spermatid differentiation

cell development [inference]

germ cell development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

negative regulation of endoplasmic reticulum calcium ion concentration

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

negative regulation of endoplasmic reticulum calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

negative regulation of endoplasmic reticulum calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

negative regulation of endoplasmic reticulum calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

negative regulation of endoplasmic reticulum calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

negative regulation of endoplasmic reticulum calcium ion concentration

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

cellular response to virus

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

response to salt stress

response to wounding [inference]

response to axon injury

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

response to topologically incorrect protein [inference]

response to unfolded protein [inference]

cellular response to unfolded protein

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

cellular response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

cellular response to virus

response to abiotic stimulus [inference]

response to osmotic stress [inference]

response to salt stress

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

response to ionizing radiation [inference]

response to gamma radiation

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

response to chemical [inference]

response to toxic substance

response to organic substance [inference]

response to topologically incorrect protein [inference]

response to unfolded protein [inference]

cellular response to unfolded protein

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of localization in cell [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of endoplasmic reticulum unfolded protein response [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

positive regulation of IRE1-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of sequestering of calcium ion [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cellular localization [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of developmental pigmentation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

positive regulation of motor neuron apoptotic process

positive regulation of epithelial cell apoptotic process

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of B cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

positive regulation of protein-containing complex assembly

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of developmental process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of reproductive process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of endoplasmic reticulum unfolded protein response [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

positive regulation of IRE1-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of response to external stimulus [inference]

regulation of response to extracellular stimulus [inference]

regulation of response to nutrient levels [inference]

regulation of nitrogen utilization

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

positive regulation of IRE1-mediated unfolded protein response

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

regulation of apoptotic process involved in development [inference]

regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway [inference]

B cell receptor apoptotic signaling pathway

extrinsic apoptotic signaling pathway

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway

signal transduction in absence of ligand [inference]

extrinsic apoptotic signaling pathway in absence of ligand

apoptotic signaling pathway

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of endoplasmic reticulum unfolded protein response [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

positive regulation of IRE1-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of DNA catabolic process [inference]

regulation of apoptotic DNA fragmentation [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

regulation of fibroblast proliferation [inference]

negative regulation of fibroblast proliferation

regulation of epithelial cell proliferation [inference]

regulation of mammary gland epithelial cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

positive regulation of motor neuron apoptotic process

positive regulation of epithelial cell apoptotic process

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of B cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

negative regulation of apoptotic process [inference]

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

positive regulation of neuron apoptotic process

positive regulation of motor neuron apoptotic process

regulation of motor neuron apoptotic process [inference]

positive regulation of motor neuron apoptotic process

regulation of epithelial cell apoptotic process [inference]

positive regulation of epithelial cell apoptotic process

regulation of apoptotic process involved in development [inference]

regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

regulation of leukocyte apoptotic process [inference]

regulation of lymphocyte apoptotic process [inference]

regulation of B cell apoptotic process [inference]

positive regulation of B cell apoptotic process

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of B cell apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of B cell apoptotic process

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

regulation of intrinsic apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

positive regulation of motor neuron apoptotic process

positive regulation of epithelial cell apoptotic process

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of B cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

positive regulation of intracellular signal transduction [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA catabolic process [inference]

positive regulation of apoptotic DNA fragmentation

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

positive regulation of motor neuron apoptotic process

positive regulation of epithelial cell apoptotic process

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of leukocyte apoptotic process [inference]

positive regulation of lymphocyte apoptotic process [inference]

positive regulation of B cell apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of intrinsic apoptotic signaling pathway

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

positive regulation of protein-containing complex assembly

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of fibroblast proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of peptidyl-serine phosphorylation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

regulation of mitochondrion organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

regulation of release of cytochrome c from mitochondria [inference]

positive regulation of release of cytochrome c from mitochondria

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

positive regulation of protein-containing complex assembly

regulation of sequestering of calcium ion [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cell cycle

regulation of cellular localization [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

positive regulation of IRE1-mediated unfolded protein response

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of endoplasmic reticulum unfolded protein response

positive regulation of IRE1-mediated unfolded protein response

regulation of pigmentation [inference]

regulation of developmental pigmentation [inference]

positive regulation of developmental pigmentation

regulation of reproductive process [inference]

positive regulation of reproductive process

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

regulation of membrane potential [inference]

negative regulation of membrane potential [inference]

negative regulation of mitochondrial membrane potential

regulation of mitochondrial membrane potential

negative regulation of mitochondrial membrane potential

regulation of membrane permeability [inference]

regulation of mitochondrial membrane permeability [inference]

positive regulation of mitochondrial membrane permeability [inference]

mitochondrial outer membrane permeabilization involved in programmed cell death [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of mitochondrial membrane permeability involved in apoptotic process [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

positive regulation of membrane permeability [inference]

positive regulation of mitochondrial membrane permeability [inference]

mitochondrial outer membrane permeabilization involved in programmed cell death [inference]

positive regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of binding [inference]

negative regulation of protein binding

regulation of binding [inference]

regulation of protein binding [inference]

negative regulation of protein binding

negative regulation of binding [inference]

negative regulation of protein binding

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
membrane	HDA	19946888
BAK complex	IDA	16113678
pore complex	IDA	9219694
Bcl-2 family protein complex	IDA	21199865
endoplasmic reticulum membrane	IDA	16424160

GO Hierarchy

cellular component

protein-containing complex [inference]

Bcl-2 family protein complex

membrane protein complex [inference]

pore complex

mitochondrial permeability transition pore complex

mitochondrial protein-containing complex [inference]

mitochondrial permeability transition pore complex

cellular anatomical entity [inference]

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

cell periphery

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10753914 11161816 11278245 11571294 11574543 12732850 12925958 14730312 14752512 14963330 15205477 15901672 16113678 16151013 16439990 16509771 16608847 17123957 17289999 17485524 17525735 17635912 18547146 18818304 18948948 18981409 19062087 19074440 19427863 19968986 20300062 20541605 20956295 21199865 21458670 21567405 21597469 21671007 22198199 23055042 23213219 23235460 23374347 24814347 25241761 25609812 26004684 26344567 29749471 32296183 32814053 33961781 9027312 9111042 9388232 9463381 9843949
channel activity	IBA IDA	9219694
BH domain binding
protein heterodimerization activity	IPI	9111042
identical protein binding	IPI	10620504 14963330 16113678 17024184 17289999 17668322 18547146 18835031 19062087 19074440 19767770 20360684 20541605 20850011 22198199 23374347

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

passive transmembrane transporter activity [inference]

channel activity

binding [inference]

protein binding

protein domain specific binding [inference]

BH domain binding

BH3 domain binding

death domain binding [inference]

BH3 domain binding

heat shock protein binding [inference]

Hsp70 protein binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein-folding chaperone binding [inference]

Hsp70 protein binding

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
extrinsic apoptotic signaling pathway in absence of ligand
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of apoptotic process
protein heterodimerization activity
protein homodimerization activity
regulation of apoptotic process
release of cytochrome c from mitochondria

Displaying **all 4** entries
InterPro
Bcl-2 family
Bcl-2, Bcl-2 homology region 1-3
Bcl-2-like superfamily
Bcl2-like

Disease

Disease Ontology

Displaying entries **1 - 10** of 48 in total

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DO ID	Disease Name	Source
DOID:0050827	rheumatic heart disease	Alliance of Genome Resources
DOID:0060071	pre-malignant neoplasm	Alliance of Genome Resources
DOID:0060108	brain glioma	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10286	prostate carcinoma	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:114	heart disease	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	12028	MGI:99702	MOUSE54702
Rattus norvegicus	24887	RGD:2192	RATNO17158
Danio rerio	58081	ZFIN:ZDB-GENE-000511-6	DANRE30898
Bos taurus	280730		BOVIN11480
Xenopus laevis	373637	Xenbase:XB-GENE-864814
Xenopus tropicalis	394793	Xenbase:XB-GENE-486067
Sus scrofa	396633		PIGXX28216
Ovis aries	443059		SHEEP05647
Felis catus	493837		FELCA33140
Danio rerio	503609	ZFIN:ZDB-GENE-050227-21

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements