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RAB3B, member RAS oncogene family

Summary

Gene Symbol

RAB3B

Organism

Homo sapiens (human)

External Links

NCBI Gene

5865

PubChem

5865

Alliance of Genome Resources

HGNC:9778

JoGo

RAB3B

TogoVar

RAB3B

Annotation

Keyword

3D-structure
Acetylation
Cell membrane
GTP-binding
Golgi apparatus
Hydrolase
Methylation
Phosphoprotein
Prenylation
Protein transport
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P20337

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
exocytosis	IBA
protein secretion
protein transport	IEA
antigen processing and presentation	IMP	19717423
positive regulation of dopamine uptake involved in synaptic transmission	IDA	20007772

GO Hierarchy

biological process

immune system process [inference]

antigen processing and presentation

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of vesicle size

export from cell [inference]

secretion by cell [inference]

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis

secretion [inference]

secretion by cell [inference]

organic substance transport [inference]

protein transport

protein secretion

nitrogen compound transport [inference]

protein transport

protein secretion

export from cell [inference]

secretion by cell [inference]

establishment of protein localization [inference]

protein transport

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

positive regulation of amine transport [inference]

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter uptake [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

regulation of catecholamine uptake involved in synaptic transmission [inference]

regulation of dopamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

regulation of amine transport [inference]

regulation of catecholamine uptake involved in synaptic transmission [inference]

regulation of dopamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

positive regulation of amine transport [inference]

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

regulation of vesicle-mediated transport [inference]

regulation of synaptic vesicle cycle

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

positive regulation of amine transport [inference]

positive regulation of catecholamine uptake involved in synaptic transmission [inference]

positive regulation of dopamine uptake involved in synaptic transmission

regulation of cellular process [inference]

regulation of vesicle-mediated transport [inference]

regulation of synaptic vesicle cycle

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of vesicle size

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GO Term	Evidence Code	PMID
cytoplasm	IDA	20807725
endosome	IBA
Golgi apparatus	IEA
plasma membrane	IBA
synaptic vesicle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell junction [inference]

synapse [inference]

dopaminergic synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

perinuclear region of cytoplasm

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GO Term	Evidence Code	PMID
GTPase activity	IDA	24891604
GTPase activity	IBA
protein binding	IPI	24891604 32296183 33961781
GTP binding	IEA
GDP binding	IDA	22321395

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

myosin binding [inference]

myosin V binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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