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renin binding protein

Summary

Gene Symbol

RENBP

Aliases

GlcNAc 2-epimerase
N-acetyl-D-glucosamine 2-epimerase
N-acylglucosamine 2-epimerase
RBP
RNBP

Organism

Homo sapiens (human)

External Links

NCBI Gene

5973

HGNC

9959

KEGG Gene ID

hsa:5973

PubChem

5973

Alliance of Genome Resources

HGNC:9959

Annotation

Keyword

Alternative initiation
Alternative splicing
Direct protein sequencing
Isomerase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P51606	GlcNAc 2-epimerase N-acetyl-D-glucosamine 2-epimerase Renin-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
N-acetylneuraminate catabolic process	IEA TAS	22692205
N-acetylglucosamine metabolic process	IBA
regulation of blood pressure	TAS	9285790
N-acetylmannosamine metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

sulfur compound catabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

alkanesulfonate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) metabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

sulfur compound metabolic process [inference]

alkanesulfonate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

sulfur compound catabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

6-sulfoquinovose(1-) metabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organophosphate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

cellular ketone metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

sulfur compound catabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

primary metabolic process [inference]

carbohydrate metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

secondary alcohol metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

alkanesulfonate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) metabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

cellular ketone metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organic substance metabolic process [inference]

carbohydrate metabolic process

cellular aldehyde metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

alkanesulfonate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) metabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organophosphate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

cellular ketone metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

mannosamine metabolic process [inference]

N-acetylmannosamine metabolic process

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

glucosamine-containing compound metabolic process [inference]

N-acetylglucosamine metabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

6-sulfoquinovose(1-) metabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

secondary alcohol metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

alkanesulfonate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) metabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

sulfur compound metabolic process [inference]

alkanesulfonate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

sulfur compound catabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

6-sulfoquinovose(1-) metabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

organophosphate metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

cellular ketone metabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

sulfur compound catabolic process [inference]

6-sulfoquinovose(1-) catabolic process [inference]

6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	TAS
extracellular exosome	HDA	19056867

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
N-acylglucosamine 2-epimerase activity	IBA IDA IMP ISS	10502668 12499362 9990133
peptidase inhibitor activity	IBA IDA	9990133
sulfoquinovose isomerase activity
endopeptidase inhibitor activity	TAS	9285790
protein binding	IPI	32296183

GO Hierarchy

molecular function

catalytic activity [inference]

isomerase activity [inference]

racemase and epimerase activity [inference]

racemase and epimerase activity, acting on carbohydrates and derivatives [inference]

N-acylglucosamine 2-epimerase activity

sulfoquinovose isomerase activity

binding [inference]

protein binding

identical protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity

endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity

endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity

endopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000102032

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K01787

Name

N-acylglucosamine 2-epimerase [EC:5.1.3.8]

References

9990133

Rhea

RHEA:19033

an N-acyl-D-glucosamine

an N-acyl-D-mannosamine

Enzyme

5.1.3.8

PMID

Disease

Disease Ontology

Displaying entries **1 - 10** of **234** in total

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DO ID	Disease Name	Source
DOID:0110108	atrial heart septal defect 3	DisGeNET
DOID:0050332	enlarged vestibular aqueduct	DisGeNET
DOID:0050523	adult T-cell leukemia/lymphoma	DisGeNET
DOID:0050782	Zollinger-Ellison syndrome	DisGeNET
DOID:0060224	atrial fibrillation	DisGeNET
DOID:0060262	gallbladder disease	DisGeNET
DOID:0060891	Parkinson's disease 19A	DisGeNET
DOID:0060895	Parkinson's disease 4	DisGeNET
DOID:0060896	Parkinson's disease 23	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET

Ortholog

Displaying entries **1 - 10** of 56 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	791728	ZFIN:ZDB-GENE-041212-34	DANRE43026
Ictalurus punctatus	108265476		ICTPU29334
Salmo trutta	115168994		SALTR75902
Gadus morhua	115552854		GADMO00796
Oryzias latipes	101162760		ORYLA16230
Oreochromis niloticus	100697984		ORENI36182
Sparus aurata	115584895		SPAAU53104
Xenopus laevis	734433	Xenbase:XB-GENE-977428
Xenopus tropicalis	100127793	Xenbase:XB-GENE-977425
Pseudonaja textilis	113443293		PSETE15772

GlyTouCan

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GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements