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coagulation factor XIII A1 chain

Summary

Gene Symbol

F13a1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

60327

PubChem

60327

Alliance of Genome Resources

RGD:621495

Annotation

Keyword

Acetylation
Acyltransferase
Blood coagulation
Calcium
Cytoplasm
Glycoprotein
Metal-binding
Reference proteome
Secreted
Zymogen

Proteins

Displaying **all 3** entries
UniProt	Protein Name
G3V811
O08619	Protein-glutamine gamma-glutamyltransferase A chain Transglutaminase A chain
A6J7C8

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
blood coagulation	ISO
peptide cross-linking	ISS
peptide cross-linking	ISO
blood coagulation, fibrin clot formation	ISS
blood coagulation, fibrin clot formation	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, fibrin clot formation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, fibrin clot formation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, fibrin clot formation

macromolecule modification [inference]

protein modification process [inference]

peptide cross-linking

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, fibrin clot formation

multicellular organismal process [inference]

coagulation [inference]

blood coagulation

biological regulation [inference]

regulation of biological quality [inference]

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein-glutamine gamma-glutamyltransferase activity	ISS
protein-glutamine gamma-glutamyltransferase activity	ISO
protein-glutamine gamma-glutamyltransferase activity	IBA
protein-glutamine gamma-glutamyltransferase activity	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

protein-glutamine gamma-glutamyltransferase activity

catalytic activity, acting on a protein [inference]

protein-glutamine gamma-glutamyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transglutaminase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
metal ion binding
protein-glutamine gamma-glutamyltransferase activity

Displaying **all 9** entries
InterPro
Immunoglobulin E-set
Immunoglobulin-like fold
Papain-like cysteine peptidase superfamily
Protein-glutamine gamma-glutamyltransferase, animal
Transglutaminase, C-terminal domain superfamily
Transglutaminase, C-terminal
Transglutaminase, N-terminal
Transglutaminase-like superfamily
Transglutaminase-like

Ortholog

Displaying entries **1 - 10** of 87 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2162	ZFIN:ZDB-GENE-030131-9634	HUMAN83011
Drosophila melanogaster	9333	FB:FBgn0031975
Drosophila melanogaster	21817	FB:FBgn0031975
Drosophila melanogaster	56083	FB:FBgn0031975
Danio rerio	60327	ZFIN:ZDB-GENE-060929-1250
Mus musculus	74145	ZFIN:ZDB-GENE-060929-1250	MOUSE12300
Pan troglodytes	462413		PANTR37160
Canis lupus familiaris	478711		CANLF13700
Danio rerio	561287		DANRE39878
Bos taurus	617881		BOVIN19270