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ribonuclease A family member 1, pancreatic

Summary

Gene Symbol

RNASE1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6035

PubChem

6035

Alliance of Genome Resources

HGNC:10044

JoGo

RNASE1

TogoVar

RNASE1

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Endonuclease
Glycoprotein
Lyase
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P07998	HP-RNase RIB-1 RNase UpI-1 Ribonuclease 1 Ribonuclease A
W0UV93

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
defense response to Gram-positive bacterium	IBA
defense response to virus	IDA	9826755

GO Hierarchy

biological process

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to symbiont [inference]

defense response to virus

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to symbiont [inference]

defense response to virus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region
extracellular exosome	HDA	23533145

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleic acid binding	IEA
endonuclease activity
ribonuclease A activity	IEA
RNA nuclease activity	IDA	9826755
RNA nuclease activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity

RNA endonuclease activity [inference]

RNA endonuclease activity, producing 3'-phosphomonoesters [inference]

ribonuclease A activity

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [inference]

RNA endonuclease activity, producing 3'-phosphomonoesters [inference]

ribonuclease A activity

RNA nuclease activity

RNA endonuclease activity [inference]

RNA endonuclease activity, producing 3'-phosphomonoesters [inference]

ribonuclease A activity

lyase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity

RNA endonuclease activity [inference]

RNA endonuclease activity, producing 3'-phosphomonoesters [inference]

ribonuclease A activity

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding

Gene Ontology information from NCBI Gene and UniProt.

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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