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phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

Summary

Gene Symbol

PIP4K2A

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 608414
KEGG Gene ID: cfa:608414
PubChem: 608414

Annotation

Keyword

ATP-binding
Cell membrane
Kinase
Lysosome
Nucleus
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8C0NSL6	1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha Diphosphoinositide kinase 2-alpha Phosphatidylinositol 5-phosphate 4-kinase type II alpha PtdIns(5)P-4-kinase isoform 2-alpha
A0A8I3NH64	1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha Diphosphoinositide kinase 2-alpha Phosphatidylinositol 5-phosphate 4-kinase type II alpha PtdIns(5)P-4-kinase isoform 2-alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol kinase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

phosphatidylinositol kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphatidylinositol kinase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatidylinositol 5-phosphate 4-kinase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
1-phosphatidylinositol-5-phosphate 4-kinase activity
ATP binding
kinase activity
nucleotide binding
phosphatidylinositol kinase activity
phosphorylation
transferase activity

Displaying **all 4** entries
InterPro
Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
Phosphatidylinositol-4-phosphate 4/5-kinase, core
Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
Phosphatidylinositol-4/5-phosphate 5/4-kinase

KEGG BRITE Database

Orthology

K00920

Name

1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]

References

7852364

Rhea

RHEA:12280

ATP + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)

H⁺ + ADP + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)

Enzyme

2.7.1.149

PMID

9367159

Ortholog

Displaying entries **31 - 40** of **105** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Mustela putorius furo	101681531	9669_0:0025b0
Ficedula albicollis	101812492		FICAL00904
Melopsittacus undulatus	101876512		MELUD01804
Chrysemys picta bellii	101938310		CHRPI00427
Capra hircus	102169193		CAPHI03384
Myotis lucifugus	102417618		MYOLU08384
Pelodiscus sinensis	102450551		PELSI18024
Panthera tigris	102949397	9694_0:001f75
Callorhinchus milii	103176337		CALMI09756
Chlorocebus sabaeus	103238000		CHLSB17621

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Acknowledgements