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phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

Summary

Gene Symbol

PIP4K2A

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 608414
KEGG Gene ID: cfa:608414
PubChem: 608414

Annotation

Keyword

ATP-binding
Cell membrane
Kinase
Lysosome
Nucleus
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8C0NSL6	1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha Diphosphoinositide kinase 2-alpha Phosphatidylinositol 5-phosphate 4-kinase type II alpha PtdIns(5)P-4-kinase isoform 2-alpha
A0A8I3NH64	1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha Diphosphoinositide kinase 2-alpha Phosphatidylinositol 5-phosphate 4-kinase type II alpha PtdIns(5)P-4-kinase isoform 2-alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol kinase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

phosphatidylinositol kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphatidylinositol kinase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatidylinositol 5-phosphate 4-kinase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
1-phosphatidylinositol-5-phosphate 4-kinase activity
ATP binding
kinase activity
nucleotide binding
phosphatidylinositol kinase activity
phosphorylation
transferase activity

Displaying **all 4** entries
InterPro
Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
Phosphatidylinositol-4-phosphate 4/5-kinase, core
Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
Phosphatidylinositol-4/5-phosphate 5/4-kinase

KEGG BRITE Database

Orthology

K00920

Name

1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]

References

7852364

Rhea

RHEA:12280

ATP + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)

H⁺ + ADP + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)

Enzyme

2.7.1.149

PMID

9367159

Ortholog

Displaying entries **81 - 90** of **105** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Phoca vitulina	116645580	9720_0:003041
Chelonoidis abingdonii	116822065		CHEAB03639
Lontra canadensis	116881203	76717_0:0031df
Mirounga leonina	118021510	9715_0:002a68
Halichoerus grypus	118535955	9711_0:004f94
Balaenoptera musculus	118890661		BALMU28855
Hyaena hyaena	120232357	95912_0:0013c5
Puma yagouaroundi	121014721	1608482_0:003499
Vulpes lagopus	121496864	494514_0:002684
Panthera leo	122223961	9689_0:00207b	PANLE18321

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OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements