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MIRAGE
Rho associated coiled-coil containing protein kinase 1
Summary
- Gene Symbol
-
- ROCK1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Apoptosis
- Cell membrane
- Cell projection
- Coiled coil
- Cytoskeleton
- Direct protein sequencing
- Golgi apparatus
- Magnesium
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Serine/threonine-protein kinase
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| Q13464 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitotic cytokinesis | ||
| epithelial to mesenchymal transition | ||
| aortic valve morphogenesis | ||
| apical constriction | ||
| chromatin remodeling |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular catabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular catabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| ruffle | ||
| extracellular region | ||
| cytoplasm | ||
| centriole |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase activity |
|
|
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| 3-phosphoinositide-dependent protein kinase activity |
GO Hierarchy
- 3-phosphoinositide-dependent protein kinase activity
- DNA-dependent protein kinase activity
- AMP-activated protein kinase activity
- eukaryotic translation initiation factor 2alpha kinase activity
- ribosomal protein S6 kinase activity
- histone H3S10 kinase activity
- histone H3T11 kinase activity
- histone H3T6 kinase activity
- histone H2AXS139 kinase activity
- histone H3S28 kinase activity
- histone H4S1 kinase activity
- histone H2AS1 kinase activity
- histone H2BS14 kinase activity
- histone H3T3 kinase activity
- histone H2AS121 kinase activity
- Rho-dependent protein serine/threonine kinase activity
- histone H2BS36 kinase activity
- histone H3S57 kinase activity
- histone H3T45 kinase activity
- histone H2AT120 kinase activity
- tau-protein kinase activity
- protein serine kinase activity
- 3-phosphoinositide-dependent protein kinase activity
- DNA-dependent protein kinase activity
- AMP-activated protein kinase activity
- eukaryotic translation initiation factor 2alpha kinase activity
- ribosomal protein S6 kinase activity
- histone H3S10 kinase activity
- histone H3T11 kinase activity
- histone H3T6 kinase activity
- histone H2AXS139 kinase activity
- histone H3S28 kinase activity
- histone H4S1 kinase activity
- histone H2AS1 kinase activity
- histone H2BS14 kinase activity
- histone H3T3 kinase activity
- histone H2AS121 kinase activity
- Rho-dependent protein serine/threonine kinase activity
- histone H2BS36 kinase activity
- histone H3S57 kinase activity
- histone H3T45 kinase activity
- histone H2AT120 kinase activity
- tau-protein kinase activity
- protein serine kinase activity
- 3-phosphoinositide-dependent protein kinase activity
- DNA-dependent protein kinase activity
- AMP-activated protein kinase activity
- eukaryotic translation initiation factor 2alpha kinase activity
- ribosomal protein S6 kinase activity
- histone H3S10 kinase activity
- histone H3T11 kinase activity
- histone H3T6 kinase activity
- histone H2AXS139 kinase activity
- histone H3S28 kinase activity
- histone H4S1 kinase activity
- histone H2AS1 kinase activity
- histone H2BS14 kinase activity
- histone H3T3 kinase activity
- histone H2AS121 kinase activity
- Rho-dependent protein serine/threonine kinase activity
- histone H2BS36 kinase activity
- histone H3S57 kinase activity
- histone H3T45 kinase activity
- histone H2AT120 kinase activity
- tau-protein kinase activity
- protein serine kinase activity
molecular function
catalytic activity [inference]
transferase activity [inference]
transferase activity, transferring phosphorus-containing groups [inference]
kinase activity [inference]
protein kinase activity
protein serine/threonine kinase activity
histone kinase activity [inference]
phosphotransferase activity, alcohol group as acceptor [inference]
protein kinase activity
protein serine/threonine kinase activity
histone kinase activity [inference]
catalytic activity, acting on a protein [inference]
protein kinase activity
protein serine/threonine kinase activity
histone kinase activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- rho-associated protein kinase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| Rho protein signal transduction |
| Rho-dependent protein serine/threonine kinase activity |
| actin cytoskeleton organization |
| actomyosin structure organization |
| kinase activity |
| metal ion binding |
| mitotic cytokinesis |
| nucleotide binding |
| phosphorylation |
