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MIRAGE
ribosomal protein S6 kinase B1

Summary
Gene Symbol
  • RPS6KB1
Organism
Homo sapiens (human)
NCBI Gene
6198
PubChem
6198
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Alternative initiation
  • Alternative splicing
  • Apoptosis
  • Cell cycle
  • Cytoplasm
  • Mitochondrion outer membrane
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Serine/threonine-protein kinase
  • Synaptosome
  • Translation regulation
Proteins
Displaying 1 entry
UniProt Protein Name
P23443
  • 70 kDa ribosomal protein S6 kinase 1
  • Ribosomal protein S6 kinase I
  • Serine/threonine-protein kinase 14A
  • p70 ribosomal S6 kinase alpha
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 44 in total
GO Term Evidence Code PMID
response to tumor necrosis factor
germ cell development
response to ethanol
apoptotic process
positive regulation of TORC1 signaling
GO Hierarchy
Displaying entries 1 - 5 of 12 in total
GO Term Evidence Code PMID
protein phosphatase 2A binding
ATP binding
protein serine/threonine/tyrosine kinase activity
protein serine/threonine kinase activity
protein serine kinase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
kinase
Functional Category
  • E: Amino acid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • T: Signal transduction mechanisms
Displaying all 5 entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
transferase activity
Displaying all 6 entries
InterPro
AGC-kinase, C-terminal
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase, C-terminal
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site
Disease
Disease Ontology
Displaying entries 1 - 10 of 11 in total
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:12236 primary biliary cholangitis
DOID:12930 dilated cardiomyopathy
DOID:2018 hyperinsulinism
DOID:219 colon cancer
DOID:4194 glucose metabolism disease
DOID:5844 myocardial infarction
DOID:767 muscular atrophy
DOID:898 autosomal dominant polycystic kidney disease
DOID:9352 type 2 diabetes mellitus
Ortholog
Displaying entries 1 - 10 of 79 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
38654 FB:FBgn0283472
72508 MGI:1270849 MOUSE06184
83840 RGD:620683 RATNO03573
176554 WB:WBGene00012929
394276 Xenbase:XB-GENE-864871
394347 Xenbase:XB-GENE-17345632
394938 Xenbase:XB-GENE-482409
404181 BOVIN12185
406349 ZFIN:ZDB-GENE-040426-2038
468426 9598_0:00437c PANTR15075
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025