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ribonucleotide reductase catalytic subunit M1

Summary

Gene Symbol

RRM1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6240

PubChem

6240

Alliance of Genome Resources

HGNC:10451

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Allosteric enzyme
Cytoplasm
Deoxyribonucleotide synthesis
Disulfide bond
Oxidoreductase
Phosphoprotein
Progressive external ophthalmoplegia
Proteomics identification
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
E9PL69
P23921	Ribonucleoside-diphosphate reductase subunit M1 Ribonucleotide reductase large subunit
B4E0I8
B4DXD1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

1

2

3

4

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GO Term	Evidence Code	PMID
DNA synthesis involved in DNA repair	NAS	10716435
pyrimidine nucleobase metabolic process	IEA
mitochondrial DNA replication	IMP	17486094
DNA repair	IDA	11719458
male gonad development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

organophosphate biosynthetic process [inference]

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate metabolic process [inference]

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate metabolic process [inference]

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organophosphate biosynthetic process [inference]

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate metabolic process [inference]

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organophosphate biosynthetic process [inference]

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

carbohydrate derivative metabolic process [inference]

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate metabolic process [inference]

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

organophosphate biosynthetic process [inference]

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

cellular process [inference]

cell population proliferation [inference]

neural precursor cell proliferation [inference]

cell proliferation in forebrain

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate metabolic process [inference]

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate metabolic process [inference]

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

organophosphate biosynthetic process [inference]

deoxyribose phosphate biosynthetic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

deoxyribonucleotide metabolic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide metabolic process [inference]

2'-deoxyribonucleotide biosynthetic process

nucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate metabolic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication [inference]

mitochondrial DNA replication

DNA repair

mitochondrial DNA metabolic process [inference]

mitochondrial DNA replication

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

deoxyribonucleotide biosynthetic process

2'-deoxyribonucleotide biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization [inference]

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization [inference]

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure development [inference]

animal organ development [inference]

gonad development [inference]

male gonad development

reproductive structure development [inference]

gonad development [inference]

male gonad development

retina development in camera-type eye

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle process [inference]

positive regulation of G0 to G1 transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle process [inference]

positive regulation of G0 to G1 transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of G0 to G1 transition [inference]

positive regulation of G0 to G1 transition

positive regulation of cell cycle process [inference]

positive regulation of G0 to G1 transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle process [inference]

positive regulation of G0 to G1 transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

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GO Term	Evidence Code	PMID
nuclear envelope	IEA
mitochondrion	IEA
cytosol	TAS
cytosol	IDA	18997010
ribonucleoside-diphosphate reductase complex	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

oxidoreductase complex [inference]

ribonucleoside-diphosphate reductase complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

ciliary basal body

cytosol

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

cell body [inference]

neuronal cell body

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GO Term	Evidence Code	PMID
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	ISS
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IBA
protein binding	IPI	17726094 21336276 22632967 28514442 32296183 33961781
ATP binding	IBA
identical protein binding	IPI	17726094 21336276 25416956

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH or CH2 groups [inference]

oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor [inference]

ribonucleoside-diphosphate reductase activity

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

binding [inference]

protein binding

protein domain specific binding [inference]

disordered domain specific binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE

Functional Category

F: Nucleotide transport and metabolism
K: Transcription
L: Replication, recombination and repair

Displaying **all 5** entries
Gene Ontology
ATP binding
catalytic activity
deoxyribonucleotide biosynthetic process
nucleotide binding
oxidoreductase activity

Displaying **all 6** entries
InterPro
ATP-cone domain
Ribonucleoside-diphosphate reductase large subunit
Ribonucleotide reductase R1 subunit, N-terminal
Ribonucleotide reductase large subunit, C-terminal
Ribonucleotide reductase large subunit, N-terminal
Ribonucleotide reductase, class I, alpha subunit, C-terminal

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:12558	chronic progressive external ophthalmoplegia	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	6240	Xenbase:XB-GENE-1014077
Mus musculus	20133	Xenbase:XB-GENE-1014077	MOUSE56690
Danio rerio	30740		DANRE21388
Pan troglodytes	450974		PANTR02091
Canis lupus familiaris	476823		CANLF08324
Bos taurus	505537		BOVIN07115
Rattus norvegicus	685579		RATNO21138
Macaca mulatta	717990		MACMU09599
Monodelphis domestica	100013713		MONDO24699
Equus caballus	100053126		HORSE38354

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements