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MIRAGE
ryanodine receptor 3
Summary
- Gene Symbol
-
- RYR3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium channel
- Calmodulin-binding
- Ligand-gated ion channel
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Sarcoplasmic reticulum
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0U1RRH1 |
|
| Q15413 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion transport | ||
| intracellular calcium ion homeostasis | ||
| striated muscle contraction | ||
| release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ||
| calcium-mediated signaling |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| smooth endoplasmic reticulum | ||
| membrane | ||
| Z disc | ||
| sarcoplasmic reticulum membrane | ||
| sarcoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| ryanodine-sensitive calcium-release channel activity | ||
| ryanodine-sensitive calcium-release channel activity | ||
| ryanodine-sensitive calcium-release channel activity | ||
| calcium ion binding | ||
| calmodulin binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- ryanodine receptor
- Functional Category
-
- K: Transcription
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ryanodine/Inositol 1,4,5-trisphosphate receptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081352 | congenital myopathy 20 | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6261 | FB:FBgn0011286 | ||
| 6262 | FB:FBgn0011286 | ||
| 6263 | Xenbase:XB-GENE-17336712 | ||
| 20190 | FB:FBgn0011286 | ||
| 20191 | FB:FBgn0011286 | ||
| 20192 | MOUSE35396 | ||
| 453296 | PANTR09866 | ||
| 689560 | FB:FBgn0011286 | ||
| 694996 | MACMU42343 | ||
| 100009545 | RABIT06213 |
